GRIN1 Antibody

ArtNr	OAAF01393
Hersteller	AVIVA Systems Biology
Menge	100 ug
Kategorie	Neuroscience Molecular Targets for Neuroscience Neural Signaling Antibodies Immunohistochemistry Western Blot ELISA Immunofluorescence Primary Antibodies Immunostaining
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	WB, IF, IHC, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Citations	Foldes R.L., Gene 131:293-298(1993). Karp S.J., J. Biol. Chem. 268:3728-3733(1993). Planells-Cases R., Proc. Natl. Acad. Sci. U.S.A. 90:5057-5061(1993).
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	GluN1;glutamate [NMDA] receptor subunit zeta-1;glutamate receptor ionotropic,NMDA 1;glutamate receptor,ionotropic,N-methyl D-aspartate 1;MRD8;NDHMSD;NDHMSR;NMDA1;NMDAR1;NMD-R1;N-methyl-D-aspartate receptor channel,subunit zeta-1;N-methyl-D-aspartate receptor subunit NR1;NR1;putative NMDtranscript(altAcc_e2).
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Applications	Enzyme-linked immunosorbent assay\|Immunofluorescence\|Immunohistochemistry\|Immunohistochemistry-Paraffin\|Western blot
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Molecular Weight	105 kDa
Manufacturer - Application Additional Information	WB: 1:500~1:3000; IHC: 1:50~1:100; ELISA: 1:20000
Gene symbol	GRIN1
Gene Fullname	glutamate ionotropic receptor NMDA type subunit 1
Product format	Liquid
Reconstitution and storage	-20°C
Description of target	Component of NMDA receptor complexes that function as heterotetrameric, ligand-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Channel activation requires binding of the neurotransmitter glutamate to the epsilon subunit, glycine binding to the zeta subunit, plus membrane depolarization to eliminate channel inhibition by Mg(2+) (PubMed:7685113, PubMed:28126851, PubMed:26919761, PubMed:26875626, PubMed:28105280). Sensitivity to glutamate and channel kinetics depend on the subunit composition (PubMed:26919761).
Protein accession_num	NP_000823.4
Protein name	Glutamate receptor ionotropic, NMDA 1
Clonality	Polyclonal
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen	The antiserum was produced against synthesized peptide derived from human NMDAR1.
Dilution	The optimal working dilution should be determined by the end user.
Manufacturer - Specificity	NMDAR1 (Ab-897) antibody detects endogenous levels of total NMDAR1 protein.
Formulation	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

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Menge: 100 ug

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Lieferung vsl. bis 29.01.2026

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