MAP3K11 Antibody

ArtNr	OAAF01646
Hersteller	AVIVA Systems Biology
Menge	100 ug
Kategorie	Oncology Neuroscience Neural Lineage Markers Molecular Targets for Neuroscience Neural Signaling Antibodies By Cell Type Blastoma Carcinoma Glioma Hematology Leukemia Lymphoma Myeloma Melanoma Sarcoma Cell Biology Cell Status Adenocarcinoma Immunohistochemistry ELISA Immunofluorescence Senescence Primary Antibodies Astrocytoma By Organ Bladder Cancer Immunostaining Glial Cell Markers
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	IF, IHC, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Citations	Gallo K.A., J. Biol. Chem. 269:15092-15100(1994). Ing Y.L., Oncogene 9:1745-1750(1994). Leung I.W.L., J. Biol. Chem. 273:32408-32415(1998).
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	MEKK11;mitogen-activated protein kinase kinase kinase 11;mixed lineage kinase 3;MLK3;MLK-3;protein-tyrosine kinase PTK1;PTK1;SH3 domain-containing proline-rich kinase;SPRK;src-homology 3 domain-containing proline-rich kinase.
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Applications	Enzyme-linked immunosorbent assay\|Immunofluorescence\|Immunohistochemistry-Paraffin
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Molecular Weight	92 kDa
Manufacturer - Application Additional Information	IHC: 1:50~1:100; ELISA: 1:20000
Gene symbol	MAP3K11
Gene Fullname	mitogen-activated protein kinase kinase kinase 11
Product format	Liquid
Reconstitution and storage	-20°C
Description of target	Activates the JUN N-terminal pathway. Required for serum-stimulated cell proliferation and for mitogen and cytokine activation of MAPK14 (p38), MAPK3 (ERK) and MAPK8 (JNK1) through phosphorylation and activation of MAP2K4/MKK4 and MAP2K7/MKK7. Plays a role in mitogen-stimulated phosphorylation and activation of BRAF, but does not phosphorylate BRAF directly. Influences microtubule organization during the cell cycle.
Protein accession_num	NP_002410.1
Protein name	Mitogen-activated protein kinase kinase kinase 11
Clonality	Polyclonal
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen	The antiserum was produced against synthesized peptide derived from human MLK3.
Dilution	The optimal working dilution should be determined by the end user.
Manufacturer - Specificity	MLK3 antibody detects endogenous levels of total MLK3 protein.
Formulation	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

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Menge: 100 ug

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Lieferung vsl. bis 13.11.2025

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