Vergleich

MARK3 Antibody

ArtNr OAAF02209
Hersteller AVIVA Systems Biology
Menge 100 ug
Kategorie
Typ Antibody Polyclonal
Format Liquid
Applikationen WB, IF, IHC, ICC, ELISA
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host Rabbit
Citations Peng C.Y., Cell Growth Differ. 9:197-208(1998).
Sun T.-Q., Nat. Cell Biol. 3:628-636(2001).
Wissing J., Mol. Cell. Proteomics 6:537-547(2007)
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias cdc25C-associated protein kinase 1;CTAK1;C-TAK1;ELKL motif kinase 2;EMK-2;KP78;MAP/microtubule affinity-regulating kinase 3;Par-1a;PAR1A;protein kinase STK10;ser/Thr protein kinase PAR-1;serine/threonine-protein kinase p78;VIPB.
Versandbedingung Gekühlt
Lieferbar
Manufacturer - Type
Polyclonal Antibody
Manufacturer - Applications
Enzyme-linked immunosorbent assay|Immunocytochemistry|Immunofluorescence|Immunohistochemistry|Immunohistochemistry-Paraffin|Western blot
Manufacturer - Category
Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature
Wet Ice
Molecular Weight
86 kDa
Manufacturer - Application Additional Information
WB: 1:500~1:3000; IHC: 1:50~1:100; ELISA: 1:5000
Gene symbol
MARK3
Gene Fullname
microtubule affinity regulating kinase 3
Product format
Liquid
Reconstitution and storage
-20°C
Description of target
Serine/threonine-protein kinase (PubMed:23666762). Involved in the specific phosphorylation of microtubule-associated proteins for MAP2 and MAP4. Phosphorylates the microtubule-associated protein MAPT/TAU (PubMed:23666762). Phosphorylates CDC25C on 'Ser-216'. Regulates localization and activity of some histone deacetylases by mediating phosphorylation of HDAC7, promoting subsequent interaction between HDAC7 and 14-3-3 and export from the nucleus (PubMed:16980613). Negatively regulates the Hippo signaling pathway and antagonizes the phosphorylation of LATS1. Cooperates with DLG5 to inhibit the kinase activity of STK3/MST2 toward LATS1 (PubMed:28087714).
Protein accession_num
NP_001122390.1
Protein name
MAP/microtubule affinity-regulating kinase 3
Clonality
Polyclonal
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen
The antiserum was produced against synthesized peptide derived from human MARK3.
Dilution
The optimal working dilution should be determined by the end user.
Manufacturer - Specificity
MARK3 antibody detects endogenous levels of total MARK3 protein.
Formulation
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
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