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CSNK1A1 Antibody

ArtNr OAAF02545
Hersteller AVIVA Systems Biology
Menge 100 ug
Kategorie
Typ Antibody Polyclonal
Format Liquid
Applikationen WB, IF, IHC, ICC, ELISA
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host Rabbit
Citations The MGC Project Team, Genome Res. 14:2121-2127(2004).
Sjoeblom T., Science 314:268-274(2006).
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias casein kinase I alpha S-like;casein kinase I isoform alpha;casein kinase I isoform alpha-like;CK1;CK1a;CKIa;CKI-alpha;CKI-alpha-like;clock regulator kinase;down-regulated in lung cancer;epididymis secretory sperm binding protein Li 77p;HEL-S-77p;HLCDGP1;PRO2975.
Versandbedingung Gekühlt
Lieferbar
Manufacturer - Type
Polyclonal Antibody
Manufacturer - Applications
Enzyme-linked immunosorbent assay|Immunocytochemistry|Immunofluorescence|Immunohistochemistry|Immunohistochemistry-Paraffin|Western blot
Manufacturer - Category
Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature
Wet Ice
Molecular Weight
39 kDa
Manufacturer - Application Additional Information
IHC: 1:50~1:100; IF: 1:100~1:500; ELISA: 1:20000
Gene symbol
CSNK1A1|CSNK1A1L
Gene Fullname
casein kinase 1 alpha 1|casein kinase 1 alpha 1 like
Product format
Liquid
Reconstitution and storage
-20°C
Description of target
Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling (By similarity).|Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates CTNNB1 at 'Ser-45'. May phosphorylate PER1 and PER2. May play a role in segregating chromosomes during mitosis (PubMed:11955436, PubMed:1409656, PubMed:18305108). May play a role in keratin cytoskeleton disassembly and thereby, it may regulate epithelial cell migration (PubMed:23902688).
Protein accession_num
NP_001020276.1
Protein name
Casein kinase I isoform alpha|Casein kinase I isoform alpha-like
Clonality
Polyclonal
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen
The antiserum was produced against synthesized peptide derived from human CKI-alpha1/L.
Dilution
The optimal working dilution should be determined by the end user.
Manufacturer - Specificity
CKI-α1/L antibody detects endogenous levels of total CKI-α1/L protein.
Formulation
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
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