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Anti-PKC Antibody (Phospho-SER345) (OAAI00344)

ArtNr OAAI00344
Hersteller AVIVA Systems Biology
Menge 100 ug
Kategorie
Typ Antibody Polyclonal
Applikationen WB, IP
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host Rabbit
Isotype IgG
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias PID, MTA1L1
Similar products PID, MTA1L1
Lieferbar
Gene symbol
MTA2
Molecular weight
ca.90 kDa
Gene id
9219
Reconstitution and storage
The antibodies are stable for 24 months from date of receipt when stored at -20C to -70C. The antibodies can be stored at 2C to 8C for three month without detectable loss of activity.
Avoid repeated freezing-thawing cycles.
Description of target
Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. With cytotoxic dose (100 uM) of anticancer drμ g, cisdiamminedlchloroplatinum(ll) (CDDP) incubation, the phosphorylation and translocation into nuclear of PKC in cancer cells including SKBR-3 which express different PKC isoforms was found. Overexpression of PKC was reported in several hemopoietic cell lines and tumors. PKC-epsilon was considered as a full oncogenic potential.
Purification
The rabbit polyclonal Antibody is purified by Affinity Purification.
Clonality
Polyclonal
Immunogen
A synthetic peptide corresponding to the epitope -EDR-S-KSAP- with a phosphorylated Ser 345 of Human PKC.
Drywet
Wet Ice

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
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