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DARPP-32 Antibody (Phospho-Thr75) (OAEC00177)

Hersteller AVIVA Systems Biology
Kategorie
Typ Antibody Polyclonal
Specific against Human, Mouse, Rat
Format Liquid
Applikationen IF
Menge 50ug
Host Rabbit
ArtNr OAEC00177
eClass 6.1 32160702
eClass 9.0 32160702
Lieferbar
Gene symbol
PPP1R1B
Protein name
Protein phosphatase 1 regulatory subunit 1B
Molecular weight
23 kDa
Product format
Liquid. PBS (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Gene id
84152
Reconstitution and storage
Store at -20° C/1 year
Description of target
This gene encodes a bifunctional signal transduction molecule. Dopaminergic and glutamatergic receptor stimulation regulates its phosphorylation and function as a kinase or phosphatase inhibitor. As a target for dopamine, this gene may serve as a therapeutic target for neurologic and psychiatric disorders. Multiple transcript variants encoding different isoforms have been found for this gene.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized phosphopeptide derived from human DARPP-32 around the phosphorylation site of threonine 75 (A-Y-TP-P-P).
Drywet
Dry Ice

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Menge: 50ug
Lieferbar: In stock
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