TRAF3 Antibody

ArtNr	OAPB00342
Hersteller	AVIVA Systems Biology
Menge	0.1 mg
Kategorie	Oncology Neuroscience Neural Lineage Markers Metabolism Diabetes Aging & Neurological Disorders Antibodies By Cell Type Hematology Lymphoma Myeloma Cell Biology Cell Status Apoptosis Western Blot ELISA Immunocytochemistry Primary Antibodies Immunostaining Neurodegeneration Markers Immunochemistry
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	WB, ICC, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Konjugat/Tag	Unconjugated
Citations	Arch RH, Gedrich RW, and Thompson CB. Tumor necrosis factor receptor-associated factors (TRAFs) â€“ a family of adaptor proteins that regulate life and death.Genes Dev. 1998; 12:2821-30.;Cheng G, Cleary AM, Ye Z, et al. Involvement of CRAF1, a relative of TRAF, in CD40 signaling. Science 1995; 267:1494-8.;Mosialos G, Birkenbach M, Yalamanchili R, et al. The Epstein-Barr virus transforming protein LMP1 engages signaling proteins for the tumor necrosis factor receptor family. Cell 1995; 80:389-99.;van Eyndhoven WG, Gamper CJ, Cho E, et al. TRAF-3 mRNA splice-deletion variants encode isoforms that induce NF0kappaB activation. Mol. Immunol. 1999; 36:647-58.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	CAP1;CAP-1;CD40 associated protein 1;CD40 binding protein;CD40 receptor associated factor 1;CD40 receptor-associated factor 1;CD40-binding protein;CD40bp;CRAF1;IIAE5;LAP1;LMP1-associated protein 1;RING-type E3 ubiquitin transferase TRAF3;RNF118;TNF receptor-associated factor 3.
Similar products	TRAF3
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Manufacturer - Application Additional Information	TRAF3 antibody can be used for the detection of TRAF3 by Western blot at 1 - 2 ug/ml. (Optimal dilution should be determined by user)
Gene symbol	TRAF3
Gene Fullname	TNF receptor associated factor 3
Product format	Liquid. TRAF3 Antibody is supplied in PBS containing 0.02% sodium azide.
Reconstitution and storage	TRAF3 antibody can be stored at 4C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Description of target	Regulates pathways leading to the activation of NF-kappa-B and MAP kinases, and plays a central role in the regulation of B-cell survival. Part of signaling pathways leading to the production of cytokines and interferon. Required for normal antibody isotype switching from IgM to IgG. Plays a role T-cell dependent immune responses. Plays a role in the regulation of antiviral responses. Is an essential constituent of several E3 ubiquitin-protein ligase complexes. May have E3 ubiquitin-protein ligase activity and promote 'Lys-63'-linked ubiquitination of target proteins. Inhibits activation of NF-kappa-B in response to LTBR stimulation. Inhibits TRAF2-mediated activation of NF-kappa-B. Down-regulates proteolytic processing of NFKB2, and thereby inhibits non-canonical activation of NF-kappa-B. Promotes ubiquitination and proteasomal degradation of MAP3K14.
Protein accession_num	https://www.ncbi.nlm.nih.gov/protein/NP_663777
Protein name	TNF receptor-associated factor 3\|TNF receptor-associated factor 3 isoform 1 [Homo sapiens]
Clonality	Polyclonal
Purification	Affinity Purified
Immunogen	TRAF3 antibody was raised against a 15 amino acid synthetic peptide from near the amino terminus of human. The immunogen is located within amino acids 20 - 70 of TRAF3.
Homology	Human; Mouse; Rat
Concentration	1 mg/ml

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Menge: 0.1 mg

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Lieferung vsl. bis 12.02.2026

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