TOLLIP Antibody

ArtNr	OAPB00384
Hersteller	AVIVA Systems Biology
Menge	0.1 mg
Kategorie	Oncology Neuroscience Neural Lineage Markers Neuroinflammation Metabolism Diabetes Antibodies By Cell Type Carcinoma Hematology Leukemia Lymphoma Obesity Immunohistochemistry Western Blot ELISA Immunofluorescence Immunocytochemistry Primary Antibodies Immunostaining Neurodegeneration Markers Immunochemistry
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	WB, IF, IHC, ICC, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus), Chicken (Gallus gallus domesticus), Cattle (Bovine)
Host	Rabbit
Konjugat/Tag	Unconjugated
Citations	Takeda K, Kaisho T, and Akira S. Toll-like receptors. Annu. Rev. Immunol.2003; 21:335-76.;Janeway CA Jr. and Medzhitov R. Innate immune recognition. Annu. Rev. Immunol.2002; 20:197-216.;McGettrick AF and Oâ€™Neill LAJ. The expanding family of MyD88-like adaptors in Toll-like receptor signal transduction. Mol. Imm.2004; 41:577-82.;Zhang G and Ghosh S. Negative regulation of Toll-like receptor-mediated signaling by Tollip. J. Biol. Chem.2002; 277:7059-65.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	adapter protein;IL-1RAcPIP;toll-interacting protein.
Similar products	TOLLIP
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Applications	Enzyme-linked immunosorbent assay\|Immunocytochemistry\|Immunofluorescence\|Immunohistochemistry-Paraffin\|Western blot
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Manufacturer - Application Additional Information	TOLLIP antibody can be used for the detection of TOLLIP by Western blot at 1 ug/ml. (Optimal dilution should be determined by user)
Gene symbol	TOLLIP
Gene Fullname	toll interacting protein
Product format	Liquid. TOLLIP Antibody is supplied in PBS containing 0.02% sodium azide.
Reconstitution and storage	TOLLIP antibody can be stored at 4C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Description of target	Component of the signaling pathway of IL-1 and Toll-like receptors. Inhibits cell activation by microbial products. Recruits IRAK1 to the IL-1 receptor complex. Inhibits IRAK1 phosphorylation and kinase activity (PubMed:11751856). Connects the ubiquitin pathway to autophagy by functioning as a ubiquitin-ATG8 family adapter and thus mediating autophagic clearance of ubiquitin conjugates. The TOLLIP-dependent selective autophagy pathway plays an important role in clearance of cytotoxic polyQ proteins aggregates (PubMed:25042851).
Nucleotide accession_num	NM_019009.3
Protein accession_num	https://www.ncbi.nlm.nih.gov/protein/AAH18272
Protein name	Toll interacting protein [Homo sapiens]\|Toll-interacting protein
Clonality	Polyclonal
Purification	Affinity Purified
Immunogen	TOLLIP antibody was raised against a 16 amino acid synthetic peptide from near the carboxy terminus of human TOLLIP. The immunogen is located within the last 50 amino acids of TOLLIP.
Homology	Human; Mouse; Rat
Concentration	1 mg/ml

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OAPB00384-datasheet.pdf

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Menge: 0.1 mg

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Lieferung vsl. bis 12.02.2026

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