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OTUD5 Antibody

ArtNr OAPB00757
Hersteller AVIVA Systems Biology
Menge 0.1 mg
Kategorie
Typ Antibody Polyclonal
Format Liquid
Applikationen WB, IF, IHC, ELISA
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host Rabbit
Konjugat/Tag Unconjugated
Citations Kayagi N, Phung Q, Chan S, et al. DUBA: A deubiquitinase that regultes type I interferon production. Science2007; 318:1628-32.;Borodovsky A, Ovaa H, Kolli N, et al. Chemistry-based functional genomics reveals novel members of the deubiquitinating enzyme family. Chem. Biol.2002; 10:1149-59.;
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias deubiquinating enzyme A;deubiquitinating enzyme A;DUBA;MCAND;OTU domain containing 5;OTU domain-containing protein 5.
Similar products OTUD5
Versandbedingung Gekühlt
Lieferbar
Manufacturer - Type
Polyclonal Antibody
Manufacturer - Applications
Enzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry-Paraffin|Western blot
Manufacturer - Category
Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Research Areas/Immunohistochemistry, Root Catalog/Products/Primary Antibodies
Shipping Temperature
Wet Ice
Manufacturer - Application Additional Information
OTUD5 antibody can be used for detection of OTUD5 by Western blot at 1 - 2 ug/ml. (Optimal dilution should be determined by user)
Gene symbol
OTUD5
Gene Fullname
OTU deubiquitinase 5
Product format
Liquid. OTUD5 Antibody is supplied in PBS containing 0.02% sodium azide.
Reconstitution and storage
OTUD5 antibody can be stored at 4C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Description of target
Deubiquitinating enzyme that functions as negative regulator of the innate immune system. Acts via TRAF3 deubiquitination and subsequent suppression of type I interferon (IFN) production. Has peptidase activity towards 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. Can also cleave 'Lys-11'-linked ubiquitin chains (in vitro).
Protein accession_num
https://www.ncbi.nlm.nih.gov/protein/EAW50723
Protein name
OTU domain containing 5, isoform CRA_b [Homo sapiens]|OTU domain-containing protein 5
Clonality
Polyclonal
Purification
Affinity Purified
Immunogen
OTUD5 antibody was raised against a 13 amino acid synthetic peptide near the carboxy terminus of the human OTUD5. The immunogen is located within amino acids 400 - 450 of OTUD5.
Homology
Human; Mouse; Rat
Concentration
1 mg/ml

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 0.1 mg
Lieferbar: In stock
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