JMJD1A Antibody

ArtNr	OAPB00948
Hersteller	AVIVA Systems Biology
Menge	0.1 mg
Kategorie	Oncology Neuroscience Neural Lineage Markers Metabolism Diabetes Glucose Homeostasis Cholesterol & Lipid Metabolism Neural Transcription Factors Antibodies Obesity Immunohistochemistry Western Blot ELISA Immunofluorescence Cardiovascular Research Atherosclerosis Primary Antibodies By Organ Colorectal Cancer Immunostaining Other Lipid\Cholesterol Metabolism Modulators
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	WB, IF, IHC, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus), Chicken (Gallus gallus domesticus)
Host	Rabbit
Konjugat/Tag	Unconjugated
Citations	Hoog C, Schalling M, Grunder-Brundell E, et al. Analysis of a murine male germ cell-specific transcript that encodes a putative zinc finger protein. Mol. Reprod. Dev.1991; 30:173-81.;Sar A, Ponjevic D, Nguyen M, et al. Identification and characterization of demethylase JMJD1A as a gene upregulated in the human cellular response to hypoxia. Cell Tissue Res.2009; 337:223-34.;Yamane K, Toumazou C, Tsukada Y, et al. JHDM2A, a JmjC-containing H3K9 demethylase, facilitates transcription activation by androgen receptor. Cell2006; 125:483-95.;Knebel J, De Haro L, and Janknecht R. Repression of transcription by TSGA/Jmjd1a, a novel interaction partner of the ETS protein ER71. J. Cell Biochem.2006; 99:319-29.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	[histone H3]-dimethyl-L-lysine(9) demethylase 3A;JHDM2A;JHMD2A;jmjC domain-containing histone demethylation protein 2A;JMJD1;JMJD1A;jumonji C domain-containing histone demethylase 2A;jumonji domain-containing protein 1A;lysine (K)-specific demethylase 3A;lysine-specific demethylase 3A;testis-specific protein A;TSGA.
Similar products	JMJD1A
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Applications	Enzyme-linked immunosorbent assay\|Immunofluorescence\|Immunohistochemistry-Paraffin\|Western blot
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Research Areas/Immunohistochemistry, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Molecular Weight	Predicted: 147kD Observed: 147kD
Manufacturer - Application Additional Information	JMJD1A antibody can be used for detection of JMJD1A by Western blot at 1 - 2 ug/ml. (Optimal dilution should be determined by user)
Gene symbol	KDM3A
Gene Fullname	lysine demethylase 3A
Product format	Liquid. JMJD1A Antibody is supplied in PBS containing 0.02% sodium azide.
Reconstitution and storage	JMJD1A antibody can be stored at 4C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Description of target	Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Preferentially demethylates mono- and dimethylated H3 'Lys-9' residue, with a preference for dimethylated residue, while it has weak or no activity on trimethylated H3 'Lys-9'. Demethylation of Lys residue generates formaldehyde and succinate. Involved in hormone-dependent transcriptional activation, by participating in recruitment to androgen-receptor target genes, resulting in H3 'Lys-9' demethylation and transcriptional activation. Involved in spermatogenesis by regulating expression of target genes such as PRM1 and TNP1 which are required for packaging and condensation of sperm chromatin. Involved in obesity resistance through regulation of metabolic genes such as PPARA and UCP1.
Protein accession_num	https://www.ncbi.nlm.nih.gov/protein/NP_060903
Protein name	Lysine-specific demethylase 3A\|lysine-specific demethylase 3A [Homo sapiens]
Clonality	Polyclonal
Purification	Affinity Purified
Immunogen	Anti-JMJD1A antibody (5365) was raised against a peptide corresponding to 16 amino acids near the amino terminus of human JMJD1A. The immunogen is located within amino acids 50-100 of JMJD1A.
Homology	Human; Mouse; Rat
Concentration	1 mg/ml

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Menge: 0.1 mg

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Lieferung vsl. bis 11.12.2025

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