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Calretinin Antibody

ArtNr OAPC00087
Hersteller AVIVA Systems Biology
Menge 100 ul
Kategorie
Typ Antibody Polyclonal
Format Liquid
Applikationen WB, IHC
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host Sheep
Citations Attanoos RL, Dojcinov SD, Webb R, Gibbs AR. (2000) Anti-mesothelial markers in sarcomatoid mesothelioma and other spindle cell neoplasms. Histopathology.37(3):224-31.
Isaacs KR, Winsky L, Strauss KI, Jacobowitz DM. (1995) Quadruple colocalization of calretinin, calcitonin gene-related peptide, vasoactive intestinal peptide, and substance P in fibers within the villi of the rat intestine. Cell Tissue Res., 280(3):639-51.
Lukas W, Jones KA (1994) Cortical neurons containing calretinin are selectively resistant to calcium overload and excitotoxicity in vitro. Neurosci. 61(2):307-16.
Weisenhorn DMV, Weruaga-Prieto E, Celio MR (1996) Calretinin immunoreactivity in organotypic cultures of the rat cerebral cortex: effects of serum deprivation. Exp. Brain Res. 108(1):101-112.
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Versandbedingung Gekühlt
Lieferbar
Manufacturer - Type
Polyclonal Antibody
Manufacturer - Category
Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Polyclonal Antibodies/Pan Specific, Root Catalog/Products/Primary Antibodies
Shipping Temperature
Wet Ice
Molecular Weight
~29kDa
Manufacturer - Application Additional Information
The antibody has been directly tested for reactivity in rat. It is expected that this antibody will also react with human, mouse and non-human primates.
Suggested dilutions are:
WB ~ 1:1000
IHC: ~ 1:500
Gene symbol
CALB2
Product format
Liquid 100 uL antibody per vial in 10mM Tris, 100mM NaCl. Adequate amount of material to conduct 10-mini Western blots
Reconstitution and storage
Store at -20°C in undiluted aliquots; stable for at least one year after date of receipt. Avoid freeze/thaw cycles.
Description of target
Calretinin is a calcium-binding protein involved in calcium signaling. It is abundantly expressed throughout the central nervous system, retina and many other tissues. Studies have shown that calretinin may play a role in neuroprotection by buffering intracellular calcium (Lukas and Jones 1994, Weisenhorn et al., 1996). Additionally, calretinin selectively stains mesothelial cells thus making it an important marker for differentiating malignant mesothelioma from carcinomas (Attanoos et al., 2000).
Protein accession_num
NP_446440.1
Protein name
Calretinin
Clonality
Polyclonal
Purification
Protein A purified sheep serum.
Immunogen
Purified guinea pig calretinin.
Homology
Human; Mouse; Rat
Manufacturer - Specificity
Specific for the ~29 kDa calretinin protein in Western blots of rat cerebellum. The antibody also works well for Immunohistochemistry on formalin or paraformaldehyde perfused rat brain tissue sections.
Concentration
0.25 mg/mL

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ul
Lieferbar: In stock
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