CYP3A4 Antibody - middle region

Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Research Areas/Epigenetics, Root Catalog/Research Areas/Methylation, Root Catalog/Products/Primary Antibodies

Wet Ice

WB: 1:500
WB: 1:1000
IHC-P: 1:10~50
FC: 1:10~50

Liquid PBS with 0.09% (W/V) sodium azide.

CYP3A4, is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by glucocorticoids and some pharmacological agents. This enzyme is involved in the metabolism of approximately half the drugs which are are used today, including acetaminophen, codeine, cyclosporin A, diazepam and erythromycin. The enzyme also metabolizes some steroids and carcinogens.

Cytochrome P450 3A4

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

2 mg/ml