CCR3 Antibody - middle region

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Wet Ice

CCR3 is a receptor for C-C type chemokines. It belongs to family 1 of the G protein-coupled receptors. This receptor binds and responds to a variety of chemokines, including eotaxin (CCL11), eotaxin-3 (CCL26), MCP-3 (CCL7), MCP-4 (CCL13), and RANTES (CCL5). It is highly expressed in eosinophils and basophils, and is also detected in TH1 and TH2 cells, as well as in airway epithelial cells. This receptor may contribute to the accumulation and activation of eosinophils and other inflammatory cells in the allergic airway. It is also known to be an entry co-receptor for HIV-1.

CCR3

Liquid PBS with 0.09% (W/V) sodium azide.

C-C chemokine receptor type 3, C-C chemokine receptor type 3 isoform 1 [Homo sapiens], C-C chemokine receptor type 3 isoform 2 [Homo sapiens]

NP_001828.1, NP_847898.1, NP_847899.1, P51677, Q9BDS8

This antibody is purified through a protein A column, followed by peptide affinity purification.

Human