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MAGED1 Antibody - middle region (OAAB17785)

ArtNr OAAB17785
Hersteller AVIVA Systems Biology
Menge 400 ul
Kategorie
Typ Antibody Monoclonal
Format Liquid. Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
Applikationen WB
Specific against Human (Homo sapiens)
Host Mouse
Isotype IgG1 kappa
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias Melanoma-associated antigen D1, MAGE tumor antigen CCF, MAGE-D1 antigen, Neurotrophin receptor-interacting MAGE homolog, MAGED1, NRAGE
Similar products MAGED1, NRAGE, Melanoma-associated antigen D1, MAGE tumor antigen CCF, MAGE-D1 antigen, Neurotrophin receptor-interacting MAGE homolog
Lieferbar
Gene symbol
MAGED1
Molecular weight
86 kDa
Product format
Liquid. Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
Gene id
9500
Reconstitution and storage
Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
Description of target
Involved in the apoptotic response after nerve growth factor (NGF) binding in neuronal cells. Binds NGFR/p75NTR and antagonizes its association with NTRK1/TrkA, inhibits cell cycle progression, and facilitates NGFR-mediated apoptosis. May act as a regulator of the function of DLX family members. May regulate TP53/p53 transcriptional activity and inhibit cell proliferation. Enhances TP53 phosphorylation and accumulation. May enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex.
Purification
This antibody is purified through a protein G column, followed by dialysis against PBS.
Clonality
Monoclonal
Immunogen
This MAGED1 antibody is generated from a mouse immunized with a KLH conjugated synthetic peptide between 20-224 amino acids from the Central region of human MAGED1.
Drywet
Wet Ice

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 400 ul
Lieferbar: In stock
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