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PTPN6 Antibody (Phospho-Tyr564)

ArtNr OAAF00422
Hersteller AVIVA Systems Biology
Menge 100 ug
Kategorie
Typ Antibody Polyclonal
Format Liquid
Applikationen WB, ELISA
Specific against Human (Homo sapiens), Monkey (Cynomolgus, Simian)
Host Rabbit
Isotype IgG
Citations Yi T., Mol. Cell. Biol. 12:836-846(1992).
Shen S.H., Nature 352:736-739(1991).
Plutzky J., Proc. Natl. Acad. Sci. U.S.A. 89:1123-1127(1992).
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias HCP;HCPH;hematopoietic cell phosphatase;hematopoietic cell protein-tyrosine phosphatase;HPTP1C;protein-tyrosine phosphatase 1C;protein-tyrosine phosphatase SHP-1;PTP-1C;SHP1;SHP-1;SHP-1L;SH-PTP1;tyrosine-protein phosphatase non-receptor type 6.
Versandbedingung Gekühlt
Lieferbar
Manufacturer - Type
Polyclonal Antibody
Manufacturer - Category
Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Polyclonal Antibodies/Phospho Specific, Root Catalog/Products/Primary Antibodies
Shipping Temperature
Wet Ice
Molecular Weight
67 kDa
Manufacturer - Application Additional Information
WB 1:500~1:1000
ELISA 1:5000
Gene symbol
PTPN6
Gene Fullname
protein tyrosine phosphatase non-receptor type 6
Product format
Liquid. PBS (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol
Reconstitution and storage
-20°C
Description of target
Modulates signaling by tyrosine phosphorylated cell surface receptors such as KIT and the EGF receptor/EGFR. The SH2 regions may interact with other cellular components to modulate its own phosphatase activity against interacting substrates. Together with MTUS1, induces UBE2V2 expression upon angiotensin II stimulation. Plays a key role in hematopoiesis.
Protein accession_num
NP_002822.2
Protein name
Tyrosine-protein phosphatase non-receptor type 6
Clonality
Polyclonal
Purification
The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.
Immunogen
The antiserum was produced against synthesized peptide derived from human SHP-1 around the phosphorylation site of Tyr564.
Dilution
The optimal working dilution should be determined by the end user.
Manufacturer - Specificity
SHP-1 (Phospho-Tyr564) antibody detects endogenous levels of SHP-1 only when phosphorylated at tyrosine 564.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
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