IFNAR1 Antibody

ArtNr	OAAF01063
Hersteller	AVIVA Systems Biology
Menge	100 ug
Kategorie	Oncology Antibodies By Cell Type Hematology Leukemia Lymphoma Cell Biology Cell Culture Cytokines Immunohistochemistry Western Blot ELISA Immunofluorescence Immunocytochemistry Primary Antibodies Immunostaining Immunochemistry
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	WB, IF, IHC, ICC, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Citations	Uze G., Cell 60:225-234(1990). Lutfalla G., J. Biol. Chem. 267:2802-2809(1992). Abramovich C., FEBS Lett. 338:295-300(1994).
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	alpha-type antiviral protein;AVP;beta-type antiviral protein;CRF2-1;cytokine receptor class-II member 1;cytokine receptor family 2 member 1;IFNalpha/beta receptor 1;IFN-alpha/beta receptor 1;IFN-alpha-REC;IFNAR;IFNBR;IFN-R-1;IFRC;interferon (alpha,beta and omega) receptor 1;interferon alpha/beta receptor 1;interferon receptor 1;interferon-alpha/beta receptor alpha chain;interferon-beta receptor 1;type I interferon receptor 1.
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Applications	Enzyme-linked immunosorbent assay\|Immunocytochemistry\|Immunofluorescence\|Immunohistochemistry\|Immunohistochemistry-Paraffin\|Western blot
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Molecular Weight	63 kDa
Manufacturer - Application Additional Information	IHC: 1:50~1:100 IF: 1:100~1:500 ELISA: 1:20000
Gene symbol	IFNAR1
Gene Fullname	interferon alpha and beta receptor subunit 1
Product format	Liquid. phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Reconstitution and storage	-20°C
Description of target	Component of the receptor for type I interferons, including interferons alpha, IFNB1 and IFNW1 (PubMed:2153461, PubMed:7665574, PubMed:10049744, PubMed:14532120, PubMed:15337770, PubMed:21854986). Functions in general as heterodimer with IFNAR2 (PubMed:7665574, PubMed:10049744, PubMed:21854986). Type I interferon binding activates the JAK-STAT signaling cascade, and triggers tyrosine phosphorylation of a number of proteins including JAKs, TYK2, STAT proteins and the IFNR alpha- and beta-subunits themselves (PubMed:7665574, PubMed:21854986). Can form an active IFNB1 receptor by itself and activate a signaling cascade that does not involve activation of the JAK-STAT pathway (By similarity).
Protein accession_num	NP_000620.2
Protein name	Interferon alpha/beta receptor 1
Clonality	Polyclonal
Purification	The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.
Immunogen	The antiserum was produced against synthesized peptide derived from human Interferon-alpha/beta Receptor alpha chain.
Dilution	The optimal working dilution should be determined by the end user.
Manufacturer - Specificity	Interferon-alpha/beta Receptor alpha chain antibody detects endogenous levels of total Interferon-alpha/beta Receptor alpha chain protein.

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Menge: 100 ug

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Lieferung vsl. bis 13.11.2025

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