Anti-CD20 Monoclonal Antibody (OAAI00042)

MS4A1

931

CD20, a non-glycosylated protein, belongs to a member of the membrane-spanning 4A gene family. The molecular weight is at a range of ca.34-37kDa depending on the degree of the protein phosphorylation. The CD20 antigen is present on Human pre B lymphocytes and B lymphocytes at all stages of matuRation. Thus, it plays an important role in the development and differentiation of B-cells into plasma cells. Low level of CD20 expression appears on normal T lymphocytes. Combination of chemo and Humanized CD20 antibodies has been reported in clinical study of lymphoma diseases.

Monoclonal

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