ARL2 Antibody

ArtNr	OACA00582
Hersteller	AVIVA Systems Biology
Menge	100 ug
Kategorie	Oncology Neuroscience Neural Lineage Markers Neural Transcription Factors Antibodies By Cell Type Blastoma Carcinoma Glioma Hematology Leukemia Lymphoma Myeloma Melanoma Cell Biology Adenocarcinoma Cytoskeleton Western Blot ELISA Primary Antibodies Immunostaining small GTPases Arf Subfamily
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	WB, ELISA
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
Purity	Caprylic Acid Ammonium Sulfate Precipitation purified
Citations	[1] Selective amplification of additional members of the ADP-ribosylation factor (ARF) family: cloning of additional human and Drosophila ARF-like genes.'Clark J., Moore L., Krasinskas A., Way J., Battey J.F., Tamkun J.W., Kahn R.A.Proc. Natl. Acad. Sci. U.S.A. 90:8952-8956(1993) [2] The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).'The MGC Project TeamGenome Res. 14:2121-2127(2004) [3] The ARF-like 2 (ARL2)-binding protein, BART. Purification, cloning, and initial characterization.'Sharer J.D., Kahn R.A.J. Biol. Chem. 274:27553-27561(1999)
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	ADP-ribosylation factor-like 2;ADP-ribosylation factor-like protein 2;ARFL2;MRCS1.
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Gene symbol	ARL2
Gene Fullname	ADP ribosylation factor like GTPase 2
Product format	Liquid
Reconstitution and storage	-20°C or -80°C
Description of target	Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors (GEF) and GTPase-activating proteins (GAP). GTP-binding protein that does not act as an allosteric activator of the cholera toxin catalytic subunit. Regulates formation of new microtubules and centrosome integrity. Prevents the TBCD-induced microtubule destruction. Participates in association with TBCD, in the disassembly of the apical junction complexes. Antagonizes the effect of TBCD on epithelial cell detachment and tight and adherens junctions disassembly. Together with ARL2, plays a role in the nuclear translocation, retention and transcriptional activity of STAT3. Component of a regulated secretory pathway involved in Ca(2+)-dependent release of acetylcholine. Required for normal progress through the cell cycle.
Nucleotide accession_num	NM_001199745.1; NM_001667.3
Protein accession_num	NP_001186674.1; NP_001658.2
Protein name	ADP-ribosylation factor-like protein 2
Clonality	Polyclonal
Purification	Protein G Purified
Immunogen	Recombinant Human ADP-ribosylation factor-like protein 2 protein (19-184AA)
Storage Buffer	Preservative: 0.03% Proclin 300Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

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Menge: 100 ug

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