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AFG3L2 Antibody - Biotin Conjugated

AFG3L2 Antibody - Biotin Conjugated

ArtNr	OACA01139
Hersteller	AVIVA Systems Biology
Menge	100 ug
Kategorie	Antibodies Western Blot ELISA Cardiovascular Research Ischemia & Reperfusion Injury Primary Antibodies Immunostaining
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	ELISA
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Biotin
Purity	Caprylic Acid Ammonium Sulfate Precipitation
Citations	[1] Identification and characterization of AFG3L2, a novel paraplegin-related gene.'Banfi S., Bassi M.T., Andolfi G., Marchitiello A., Zanotta S., Ballabio A., Casari G., Franco B.Genomics 59:51-58(1999) [2] The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).'The MGC Project TeamGenome Res. 14:2121-2127(2004) [3] Lysine acetylation targets protein complexes and co-regulates major cellular functions.'Choudhary C., Kumar C., Gnad F., Nielsen M.L., Rehman M., Walther T., Olsen J.V., Mann M.Science 325:834-840(2009)
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	AFG3 ATPase family gene 3-like 2;AFG3 ATPase family member 3-like 2;AFG3 like AAA ATPase 2;AFG3-like protein 2;ATPase family gene 3,yeast;OPA12;paraplegin-like protein;SCA28;SPAX5.
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Gene symbol	AFG3L2
Gene Fullname	AFG3 like matrix AAA peptidase subunit 2
Product format	Liquid
Reconstitution and storage	-20°C or -80°C
Description of target	ATP-dependent protease which is essential for axonal and neuron development. In neurons, mediates degradation of SMDT1/EMRE before its assembly with the uniporter complex, limiting the availability of SMDT1/EMRE for MCU assembly and promoting efficient assembly of gatekeeper subunits with MCU (PubMed:27642048). Required for the maturation of paraplegin (SPG7) after its cleavage by mitochondrial-processing peptidase (MPP), converting it into a proteolytically active mature form (By similarity).
Nucleotide accession_num	NM_006796.2
Protein accession_num	NP_006787.2
Protein name	AFG3-like protein 2
Clonality	Polyclonal
Purification	Protein G Purified
Immunogen	Recombinant Human AFG3-like protein 2 protein (550-759AA)
Storage Buffer	Preservative: 0.03% Proclin 300Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

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Menge: 100 ug

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