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MCAM Antibody - FITC Conjugated

MCAM Antibody - FITC Conjugated

ArtNr	OACA01706
Hersteller	AVIVA Systems Biology
Menge	100 ug
Kategorie	Oncology Neuroscience Neural Lineage Markers Molecular Targets for Neuroscience Neural Adhesion Molecules Antibodies By Cell Type Blastoma Carcinoma Hematology Lymphoma Myeloma Western Blot ELISA Primary Antibodies By Organ Skin Cancer Adhesion Molecule Markers
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	WB
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	FITC
Purity	Caprylic Acid Ammonium Sulfate Precipitation purified
Citations	[1] MUC18, a marker of tumor progression in human melanoma, shows sequence similarity to the neural cell adhesion molecules of the immunoglobulin superfamily.Lehmann J.M., Riethmueller G., Johnson J.P.Proc. Natl. Acad. Sci. U.S.A. 86:9891-9895(1989) [2] Genomic organization of the melanoma-associated glycoprotein MUC18: implications for the evolution of the immunoglobulin domains.Sers C., Kirsch K., Rothbaecher U., Riethmueller G., Johnson J.P.Proc. Natl. Acad. Sci. U.S.A. 90:8514-8518(1993) [3] Identification and functional assessment of endothelial P1H12.Solovey A.N., Gui L., Chang L., Enenstein J., Browne P.V., Hebbel R.P.J. Lab. Clin. Med. 138:322-331(2001)
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	CD146;cell surface glycoprotein MUC18;cell surface glycoprotein P1H12;Gicerin;HEMCAM;melanoma adhesion molecule;Melanoma cell adhesion molecule;melanoma-associated antigen A32;melanoma-associated antigen MUC18;MelCAM;METCAM;MUC18;S-endo 1 endothelial-associated antigen.
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Gene symbol	MCAM
Gene Fullname	melanoma cell adhesion molecule
Product format	Liquid
Reconstitution and storage	-20°C or -80°C
Description of target	Plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development. Acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2/FAK1, and a transient increase in the intracellular calcium concentration.
Nucleotide accession_num	NM_006500.2
Protein accession_num	NP_006491.2
Protein name	Cell surface glycoprotein MUC18
Clonality	Polyclonal
Purification	Protein G Purified
Immunogen	Recombinant Human Cell surface glycoprotein MUC18 protein (50-646AA)
Storage Buffer	Preservative: 0.03% Proclin 300Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 100 ug

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