Goat Anti-Plasminogen Activator / PLAU Antibody (OAEB02234)

This antibody is expected to recognise both reported isoforms.

PLAU, plasminogen activator, urokinase, HGNC:9052, ATF, UPA, URK, u-PA, U-plasminogen activator, antagonist of uPA, plasminogen activator, urinary, urokinase plasminogen activator, urokinase-type plasminogen activator amino-terminal, urokinase-type plasmi

C-HFLPWIRSHTKEEN

Human

Peptide ELISA: antibody detection limit dilution 1:8000. Western Blot: Approx 48kDa band observed in lysates of human kidney fibroblast cell line HEK293 (calculated MW of 48.5kDa according to NP_002649.1). Recommended concentration: 0.3-1.0ug/ml. A minor band was also consistently observed at appox 35kDa. This band was successfully blocked by incubation with the immunising peptide, and is consistent with the B chain of Cathepsin B-mediated cleavage product of PLAU (Kobayashi et al, J Biol Chem. 1991 Mar 15, 266(8):5147-52, PMID: 1900515).