PRAM1 Antibody

ArtNr	OAEB02272
Hersteller	AVIVA Systems Biology
Menge	100 ug
Kategorie	Oncology Antibodies By Cell Type Hematology Leukemia Western Blot Primary Antibodies
Typ	Antibody Polyclonal
Applikationen	WB
Specific against	Human (Homo sapiens), Pig (Porcine, Sus scrofa domesticus)
Host	Caprine
Purity	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Sequence	DFCDPLENQPLPLGR
Citations	* Moog-Lutz C, Peterson EJ, Lutz PG, Eliason S, Cave-Riant F, Singer A, Di Gioia Y, Dmowski S, Kamens J, Cayre YE, Koretzky G.; PRAM-1 is a novel adaptor protein regulated by retinoic acid (RA) and promyelocytic leukemia (PML)-RA receptor alpha in acute promyelocytic leukemia cells.; J Biol Chem 2001 Jun 22;276(25):22375-81; Pubmed 11301322
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	PML-RAR;PML-RARA target gene encoding an Adaptor Molecule-1;PML-RARA-regulated adapter molecule 1;PRAM;PRAM-1.
Similar products	PRAM1
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Molecular Weight	74
Manufacturer - Application Additional Information	Peptide ELISA: antibody detection limit dilution 1:8000. Western Blot: Approx 90-100kDa band seen in Jurkat cell lysates. Recommended for use at 1-3ug/ml. Overnight incubation is recommended with this antibody. Please note that although the predicted MW of PRAM-1 is 79kDa, Moog-Lutz et al., (J. Biol. Chem, Jun 2001; 276: 22375 - 22381) detected aPRAM-1 migrating with an apparent molecular mass of 97 kDa and this is what we observed as well.
Gene symbol	PRAM1
Gene Fullname	PML-RARA regulated adaptor molecule 1
Product format	Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20Â°C. Minimize freezing and thawing.
Reconstitution and storage	Aliquot and store at -20C. Minimize freezing and thawing.
Protein accession_num	NP_115528.3
Protein name	PML-RARA-regulated adapter molecule 1
Clonality	Polyclonal
Purification	Ammonium Sulfate Precipitated; Affinity Purified
Immunogen	PRAM1
Homology	Human
Concentration	0.5 mg/ml

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