TNFRSF12A Antibody

ArtNr	OAPB00456
Hersteller	AVIVA Systems Biology
Menge	0.1 mg
Kategorie	Oncology Neuroscience Neural Lineage Markers Protein Aggregation, Clearance & Misfolding Antibodies By Cell Type Cell Biology Cell Status Apoptosis Flow Cytometry Immunohistochemistry Western Blot ELISA Immunofluorescence Primary Antibodies Immunostaining Neurodegeneration Markers
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	WB, IF, IHC, ELISA
Specific against	Human (Homo sapiens)
Host	Rabbit
Konjugat/Tag	Unconjugated
Citations	Chicheportiche Y, Bourdon PR, Xu H, et al. TWEAK, a new secreted ligand in the tumor necrosis factor family that weakly induces apoptosis. J. Biol. Chem.1997; 272:32401-10.;Nakayama M, Ishidoh K, Kojima Y, et al. Fibroblast growth factor-inducible 14 mediates multiple pathways of TWEAK-induced cell death. J. Immunol. 2003; 170:341-8.;Brown SA, Richards CM, Hanscom HN, et al. The Fn14 cytoplasmic tail binds tumour-necrosis-factor-receptor-associated factors 1, 2, 3, and 5 and mediates nuclear factor-kappaB activation. Biochem. J. 2003; 371:395-403.;Feng SL, Guo Y, Factor VM, et al. The Fn14 immediate-early response gene is induced during liver regeneration and highly expressed in both human and murine hepatocellular carcinomas. Am. J. Pathol. 2000; 156:1253-61
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	CD266;FGF-inducible 14;fibroblast growth factor-inducible immediate-early response protein 14;FN14;tumor necrosis factor receptor superfamily member 12A;TWEAKR;tweak-receptor;type I transmembrane protein Fn14.
Similar products	Fn14
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Applications	Enzyme-linked immunosorbent assay\|Immunofluorescence\|Immunohistochemistry-Paraffin\|Western blot
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Manufacturer - Application Additional Information	Fn14 antibody can be used for the detection of Fn14 by Western blot at 2-4 ug/ml. (Optimal dilution should be determined by user)
Gene symbol	TNFRSF12A
Gene Fullname	TNF receptor superfamily member 12A
Product format	Liquid. Fn14 Antibody is supplied in PBS containing 0.02% sodium azide.
Reconstitution and storage	Fn14 antibody can be stored at 4C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Description of target	Receptor for TNFSF12/TWEAK. Weak inducer of apoptosis in some cell types. Promotes angiogenesis and the proliferation of endothelial cells. May modulate cellular adhesion to matrix proteins.
Nucleotide accession_num	NM_016639.2
Protein accession_num	https://www.ncbi.nlm.nih.gov/protein/NP_057723
Protein name	Tumor necrosis factor receptor superfamily member 12A\|tumor necrosis factor receptor superfamily member 12A precursor [Homo sapiens]
Clonality	Polyclonal
Purification	Affinity Purified
Immunogen	Fn14 antibody was raised against a human IgG1 Fc-tagged Fn14 protein.
Homology	Human
Concentration	1 mg/ml

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Menge: 0.1 mg

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