GFAP Antibody

ArtNr	OAEE00402
Hersteller	AVIVA Systems Biology
Menge	0.1 mg (C100)
Kategorie	Oncology Neuroscience Neural Lineage Markers Molecular Targets for Neuroscience Targets for Rodent Neurosciences Antibodies By Cell Type Blastoma Immunohistochemistry Immunoprecipitation Western Blot ELISA Immunocytochemistry Primary Antibodies Neurodegeneration Markers Microglia Markers Immunochemistry
Typ	Antibody Monoclonal
Applikationen	WB, IP, IHC, ICC
Clon	GA-5
Specific against	Human (Homo sapiens), Rat (Rattus norvegicus), Pig (Porcine, Sus scrofa domesticus)
Host	Mouse
Isotype	IgG1
Purity	> 95% (by SDS-PAGE)
Citations	Joardar A, Sen AK, Das S: Docosahexaenoic acid facilitates cell maturation and beta-adrenergic transmission in astrocytes. J Lipid Res. 2006 Mar;47(3):571-81. Guillemin GJ, Wang L, Brew BJ: Quinolinic acid selectively induces apoptosis of human astrocytes: potential rolein AIDS dementia complex. J Neuroinflammation. 2005 Jul 26;2:16. Rungger-BrÃ¤ndle E, Dosso AA, Leuenberger PM: Glial reactivity, an early feature of diabetic retinopathy. Invest Ophthalmol Vis Sci. 2000 Jun;41(7):1971-80. Perng MD, Cairns L, van den IJssel P, Prescott A, Hutcheson AM, Quinlan RA: Intermediate filament interactions can be altered by HSP27 and alphaB-crystallin. J Cell Sci. 1999 Jul;112 ( Pt 13):2099-112. Triviño A, RamÃrez JM, RamÃrez AI, Salazar JJ, GarcÃa-Sanchez J: Retinal perivascular astroglia: an immunoperoxidase study. Vision Res. 1992 Sep;32(9):1601-7. Bignami A, Eng LF, Dahl D, Uyeda C.T.: Localization of the glial fibrillary acidic protein in astrocytes by immunofluorescence. Brain Res. 1972 Aug 25;43(2):429-35. Brenner M, Johnson AB, Boespflug-Tanguy O, Rodriguez D, Goldman JE, Messing A.: Mutations in GFAP, encoding glial fibrillary acidic protein, are associated with Alexander disease. Nat Genet. 2001 Jan;27(1):117-20.
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	ALXDRD;glial fibrillary acidic protein.
Similar products	GFAP
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Type	Monoclonal Antibody
Manufacturer - Applications	Immunocytochemistry\|Immunohistochemistry-Paraffin\|Immunoprecipitation\|Western blot
Manufacturer - Category	Root Catalog/Products/Monoclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Gene symbol	GFAP
Gene Fullname	glial fibrillary acidic protein
Product format	Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Reconstitution and storage	2°C to 8°C
Description of target	GFAP, a class-III intermediate filament, is a cell-specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells.
Nucleotide accession_num	NM_001131019.2; NM_001242376.1; NM_002055.4
Protein accession_num	NP_001124491.1; NP_001229305.1; NP_002046.1
Protein name	Glial fibrillary acidic protein
Clonality	Monoclonal
Purification	Purified
Immunogen	Porcine spinal cord
Manufacturer - Specificity	The antibody GA-5 reacts with GFAP, the principal marker of astroglial cells in the central nervous system, which is specifically expressed in satellite cells in peripheral ganglia and in non myelinating Schwann cells in peripheral nerves. The GFAP protein runs on gels at ~55 kDa protein, usually associated with lower Mw bands which are thought to be proteolytic fragments and alternate transcripts from the single gene.
Formulation	Purified
Concentration	1 mg/ml
Storage Buffer	Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4

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Menge: 0.1 mg (C100)

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