TET2 Antibody

ArtNr	OAEB00839
Hersteller	AVIVA Systems Biology
Menge	100 ug
Kategorie	Oncology Antibodies By Cell Type Carcinoma Hematology Leukemia Lymphoma Melanoma Sarcoma Immunohistochemistry Primary Antibodies
Typ	Antibody Polyclonal
Applikationen	IHC
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Dog (Canine, Canis lupus familiaris)
Host	Caprine
Sequence	C-PHPQSNNDQQREGSF
Citations	Reduction of global 5-hydroxymethylcytosine is a poor prognostic factor in breast cancer patients, especially for an ER/PR-negative subtype. Breast Cancer Res. Treat. 153, 219-34 (2015). 26253945 Ten-eleven translocation 1 dysfunction reduces 5-hydroxymethylcytosine expression levels in gastric cancer cells. Oncol Lett. 15, 278-284 (2018). 29285192 Langemeijer SM, Kuiper RP, Berends M, Knops R, Aslanyan MG, Massop M, Stevens-Linders E, van Hoogen P, van Kessel AG, Raymakers RA, Kamping EJ, Verhoef GE, Verburgh E, Hagemeijer A, Vandenberghe P, de Witte T, van der Reijden BA, Jansen JH, Acquired mutations in TET2 are common in myelodysplastic syndromes. Nature Gen. 2009 Jul 41 (7): 838-42. PMID: 19483684
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Ayu17-44;Ayu17-449;E130014J05Rik;IMD75;KIAA1546;MDS;methylcytosine dioxygenase TET2;mKIAA1546;probable methylcytosine dioxygenase TET2;ten-eleven translocation 2;tet oncogene 2;tet oncogene family member 2.
Similar products	TET2
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Research Areas/Cell Biology, Root Catalog/Research Areas/Stem Cells, Root Catalog/Research Areas/Meiosis\/Mitosis\/Cell Cycle, Root Catalog/Research Areas/Immunohistochemistry, Root Catalog/Research Areas/Cell Differentiation, Root Catalog/Products/Primary Antibodies, Root Catalog/Research Areas/Cancer/Cancer Cell Cycle
Shipping Temperature	Wet Ice
Molecular Weight	224; 130
Species Tested	Human
Manufacturer - Application Additional Information	P-ELISA: Antibody detection limit dilution 1:16000IHC: In paraffin embedded Human Spleen shows nuclear staining in select splenocytes. Recommended concentration: 2-6 ug/ml.
Gene symbol	Tet2\|TET2
Gene Fullname	tet methylcytosine dioxygenase 2
Product format	Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20Â°C. Minimize freezing and thawing.
Reconstitution and storage	Aliquot and store at -20°C. Minimize freezing and thawing.
Protein accession_num	NP_001120680.1
Protein name	Methylcytosine dioxygenase TET2
Clonality	Polyclonal
Purification	Ammonium Sulfate Precipitated; Affinity Purified
Immunogen	TET2
Homology	Human, Mouse, Dog
Manufacturer - Specificity	This antibody is expected to recognize both reported isoforms (NP_001120680.1; NP_060098.3).
Concentration	0.5 mg/ml

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