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FLNA Antibody

ArtNr OAAB17757
Hersteller AVIVA Systems Biology
Menge 400 ul
Kategorie
Typ Antibody Monoclonal
Format Liquid
Applikationen WB
Specific against Human (Homo sapiens), Rat (Rattus norvegicus)
Host Mouse
Isotype IgG1
Citations Gorlin J.B., et al. J. Cell Biol. 111:1089-1105(1990).
Patrosso M.C., et al. Genomics 21:71-76(1994).
Chen E.Y., et al. Hum. Mol. Genet. 5:659-668(1996).
Li J., et al. Mol. Cell. Proteomics 9:2517-2528(2010).
Ota T., et al. Nat. Genet. 36:40-45(2004).
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias FLN,FMD,MNS,OPD,ABPX,CSBS,CVD1,FGS2,FLN1,NHBP,OPD1,OPD2,XLVD,XMVD,FLN-A,ABP-280
Similar products FLNA, Alpha-filamin, Filamin-1, Endothelial actin-binding protein, Actin-binding protein 280, Non-muscle filamin, FLN, FLN1, Filamin-A
Versandbedingung Gekühlt
Lieferbar
Manufacturer - Type
Monoclonal Antibody
Manufacturer - Category
Root Catalog/Products/Primary Antibodies
Shipping Temperature
Wet Ice
Molecular Weight
281 kDa
Manufacturer - Application Additional Information
IF: 1:25
WB: 1:4000
WB: 1:1000
Gene symbol
FLNA
Product format
Liquid. Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
Reconstitution and storage
Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
Description of target
Promotes orthogonal branching of actin filaments and links actin filaments to membrane glycoproteins. Anchors various transmembrane proteins to the actin cytoskeleton and serves as a scaffold for a wide range of cytoplasmic signaling proteins. Interaction with FLNA may allow neuroblast migration from the ventricular zone into the cortical plate. Tethers cell surface-localized furin, modulates its rate of internalization and directs its intracellular trafficking (By similarity). Involved in ciliogenesis.
Protein accession_num
NP_001104026.1, NP_001447.2
Clonality
Monoclonal
Purification
This antibody is purified through a protein G column, followed by dialysis against PBS.
Immunogen
Purified His-tagged FLNA protein was used to produced this monoclonal antibody.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 400 ul
Lieferbar: In stock
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