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Goat Anti-CMG1 / CCDC2 / IFT74 Antibody

ArtNr OAEB02484
Hersteller AVIVA Systems Biology
Menge 100 ug
Kategorie
Typ Antibody Polyclonal
Applikationen WB, IF, IHC
Specific against Human (Homo sapiens), Rat (Rattus norvegicus)
Host Caprine
Purity Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Sequence C-KTIVDALHSTSGN
Citations * Momeni P, Schymick J, Jain S, Cookson MR, Cairns NJ, Greggio E, Greenway MJ, Berger S, Pickering-Brown S, Chio A, Fung HC, Holtzman DM, Huey ED, Wassermann EM, Adamson J, Hutton ML, Rogaeva E, St George-Hyslop P, Rothstein JD, Hardiman O, Grafman J, Singleton A, Hardy J, Traynor BJ.; Analysis of IFT74 as a candidate gene for chromosome 9p-linked ALS-FTD.; BMC Neurol. 2006 Dec 13;6:44; Pubmed 17166276
* Bell SE, Mavila A, Salazar R, Bayless KJ, Kanagala S, Maxwell SA, Davis GE.; Differential gene expression during capillary morphogenesis in 3D collagen matrices: regulated expression of genes involved in basement membrane matrix assembly, cell cycle progression, cellular differentiation and G-protein signaling.; J Cell Sci. 2001 Aug;114(Pt 15):2755-73.; Pubmed 11683410
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias BBS22;capillary morphogenesis gene 1 protein;capillary morphogenesis protein 1;CCDC2;CMG1;CMG-1;coiled-coil domain containing 2;coiled-coil domain-containing protein 2;intraflagellar transport 74 homolog;intraflagellar transport protein 74 homolog.
Similar products IFT74
Versandbedingung Gekühlt
Lieferbar
Manufacturer - Type
Polyclonal Antibody
Manufacturer - Category
Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Research Areas/Immunohistochemistry, Root Catalog/Products/Primary Antibodies
Shipping Temperature
Wet Ice
Molecular Weight
69, 2
Manufacturer - Application Additional Information
Peptide ELISA: antibody detection limit dilution 1:16000.
Western Blot: Approx 70-75kDa band observed in lysates of cell line HEK293 (calculated MW of 69.2kDa according to AAK77221.1, but 51.4kDa according to NP_079379.1). The observed molecular weight corresponds to earlier findings in literature with different antibodies (Momeni et al, BMC Neurol. 2006 Dec 13; 6:44.; PMID: 17166276). Recommended concentration: 0.3-1ug/ml.
Immunohistochemistry: In paraffin embedded Human Liver shows vesicular staining in cytoplasm of hepatocytes. Recommended concentration, 5-10ug/ml.
Other Notes: Immunofluorescence: It was successfully used at 2.5mg/ml to stain rat cortical neurons (see picture and PMID: 17166276).
Gene symbol
Ift74|IFT74
Gene Fullname
intraflagellar transport 74
Product format
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
Reconstitution and storage
Aliquot and store at -20C. Minimize freezing and thawing.
Protein accession_num
NP_001092692.1
Protein name
Intraflagellar transport protein 74 homolog
Clonality
Polyclonal
Purification
Ammonium Sulfate Precipitated; Affinity Purified
Immunogen
IFT74
Homology
Human: 100%; Rabbit: 100%
Concentration
0.5 mg/ml

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
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