TYMS Antibody - C-terminal region

Polyclonal Antibody

Wet Ice

Mouse

thymidylate synthase

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

This gene encodes an enzyme that catalyzes the methylation of deoxyuridylate to deoxythymidylate using 5, 10-methylenetetrahydrofolate as a cofactor. This function maintains the thymidine-5-prime monophosphate concentration critical for DNA replication and repair. The encoded enzyme is a target for cancer chemotherapeutic agents. The majority of transcripts for this gene lack a 3' UTR. The stop codon in these transcripts is UAA, compared to the UAG found in the genome and longer transcripts, as the polyA site is located within the stop codon. A related pseudogene has been identified on chromosome 10.

NP_067263.1

Polyclonal

The immunogen is a synthetic peptide directed towards the C terminal region of mouse TYMS