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Eno1 Antibody - HRP Conjugated

ArtNr OACA00443
Hersteller AVIVA Systems Biology
Menge 100 ug
Kategorie
Typ Antibody Polyclonal
Format Liquid
Applikationen ELISA
Specific against Mouse (Murine, Mus musculus)
Host Rabbit
Isotype IgG
Konjugat/Tag HRP
Purity Caprylic Acid Ammonium Sulfate Precipitation purified
Citations [1] Limb alterations in brachypodism mice due to mutations in a new member of the TGF beta-superfamily.'Storm E.E., Huynh T.V., Copeland N.G., Jenkins N.A., Kingsley D.M., Lee S.-J.Nature 368:639-643(1994)
[2] Lineage-specific biology revealed by a finished genome assembly of the mouse.'Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S., Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., Eichler E.E., Ponting C.P.PLoS Biol. 7:E1000112-E1000112(2009)
[3] Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C.Submitted (JUL-2005)
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias b;BMP-14;bone morphogenetic protein 14;bp;brp;cartilage-derived morphogenetic protein-1;CDMP-;Cdmp-1;growth/differentiation factor 5.
Versandbedingung Gekühlt
Lieferbar
Manufacturer - Type
Polyclonal Antibody
Manufacturer - Category
Root Catalog/Products/Primary Antibodies
Shipping Temperature
Wet Ice
Gene symbol
Gdf5
Gene Fullname
growth differentiation factor 5
Product format
Liquid
Reconstitution and storage
-20°C or -80°C
Description of target
Growth factor involved in bone and cartilage formation. During cartilage development regulates differentiation of chondrogenic tissue through two pathways. Firstly, positively regulates differentiation of chondrogenic tissue through its binding of high affinity with BMPR1B and of less affinity with BMPR1A, leading to induction of SMAD1-SMAD5-SMAD8 complex phosphorylation and then SMAD protein signaling transduction (By similarity). Secondly, negatively regulates chondrogenic differentiation through its interaction with NOG (By similarity). Required to prevent excessive muscle loss upon denervation. This function requires SMAD4 and is mediated by phosphorylated SMAD1/5/8 (PubMed:24076600). Binds bacterial lipopolysaccharide (LPS) and mediates LPS-induced inflammatory response, including TNF secretion by monocytes (By similarity).
Protein name
Growth/differentiation factor 5
Clonality
Polyclonal
Purification
Protein G Purified
Immunogen
Recombinant Mouse Growth/differentiation factor 5 protein (376-495AA)
Storage Buffer
Preservative: 0.03% Proclin 300Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
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