Vergleich

Mmp13 Antibody - Biotin Conjugated

ArtNr OACA02228
Hersteller AVIVA Systems Biology
Menge 100 ug
Kategorie
Typ Antibody Polyclonal
Format Liquid
Applikationen ELISA
Specific against Mouse (Murine, Mus musculus)
Host Rabbit
Isotype IgG
Konjugat/Tag Biotin
Purity Caprylic Acid Ammonium Sulfate Precipitation purified
Citations [1] Cloning and sequencing of mouse collagenase cDNA. Divergence of mouse and rat collagenases from the other mammalian collagenases.'Henriet P., Rousseau G.G., Eeckhout Y.FEBS Lett. 310:175-178(1992)
[2] Structure of recombinant mouse collagenase-3 (MMP-13).'Botos I., Meyer E., Swanson S.M., Lemaitre V., Eeckhout Y., Meyer E.F.J. Mol. Biol. 292:837-844(1999)
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Cl;Clg;collagenase 3;collagenase-1;interstitial collagenase;matrix metalloproteinase 13;Matrix metalloproteinase-13;Mmp;Mmp1;MMP-1;MMP-13.
Versandbedingung Gekühlt
Lieferbar
Manufacturer - Type
Polyclonal Antibody
Manufacturer - Category
Root Catalog/Products/Primary Antibodies
Shipping Temperature
Wet Ice
Gene symbol
Mmp13
Gene Fullname
matrix metallopeptidase 13
Product format
Liquid
Reconstitution and storage
-20°C or -80°C
Description of target
Plays a role in the degradation of extracellular matrix proteins including fibrillar collagen, fibronectin, TNC and ACAN. Cleaves triple helical collagens, including type I, type II and type III collagen, but has the highest activity with soluble type II collagen. Can also degrade collagen type IV, type XIV and type X. May also function by activating or degrading key regulatory proteins, such as TGFB1 and CTGF. Plays a role in wound healing, tissue remodeling, cartilage degradation, bone development, bone mineralization and ossification. Required for normal embryonic bone development and ossification. Plays a role in the healing of bone fractures via endochondral ossification. Plays a role in wound healing, probably by a mechanism that involves proteolytic activation of TGFB1 and degradation of CTGF. Plays a role in keratinocyte migration during wound healing. May play a role in cell migration and in tumor cell invasion.
Protein name
Collagenase 3
Clonality
Polyclonal
Purification
Protein G Purified
Immunogen
Recombinant Mouse Collagenase 3 protein (105-472AA)
Storage Buffer
Preservative: 0.03% Proclin 300Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
lieferbar

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