Thy1 Antibody

ArtNr	OAEE00340
Hersteller	AVIVA Systems Biology
Menge	0.1 mg (C100)
Kategorie	Neuroscience Molecular Targets for Neuroscience Aging & Neurological Disorders Neural Development Antibodies Cell Biology Cell Movement Cell Adhesion Flow Cytometry Western Blot Immunocytochemistry Primary Antibodies Immunochemistry Functional Assays
Typ	Antibody Monoclonal
Applikationen	WB, FC, ICC, FA
Clon	1aG4/C5
Specific against	Mouse (Murine, Mus musculus)
Host	Mouse
Isotype	IgG3
Purity	> 95% (by SDS-PAGE)
Citations	Bradley JE, Ramirez G, Hagood JS: Roles and regulation of Thy-1, a context-dependent modulator of cell phenotype. Biofactors. 2009 May-Jun;35(3):258-65. Draber P, Zikan J, Vogtiskova M: Establishment and characterization of permanent murine hybridomas secreting monoclonal anti-thy-1 antibodies. J Immunogenet. 1980 Dec;7(6):455-74. Zikan J, Draber P, Vojtiskova M: Monoclonal IgG3 (kappa) antibodies against murine Thy-1.2 antigen produced by murine hybridomas. Differences in the specificity of the antigen binding site and in the structure of the hinge region. Folia Biol (Praha). 1982;28(6):377-94. Draberova L, Draber P: Thy-1 glycoprotein and src-like protein-tyrosine kinase p53/p56lyn are associated in large detergent-resistant complexes in rat basophilic leukemiacells. Proc Natl Acad Sci U S A. 1993 Apr 15;90(8):3611-5. Heneberg P, Lebduska P, Draberova L, Korb J, Draber P: Topography of plasma membrane microdomains and its consequences for mast cell signaling. Eur J Immunol. 2006 Oct;36(10):2795-806. Rege TA, Hagood JS: Thy-1 as a regulator of cell-cell and cell-matrix interactions in axon regeneration, apoptosis, adhesion, migration, cancer, and fibrosis. FASEB J. 2006 Jun;20(8):1045-54. Rege TA, Hagood JS: Thy-1, a versatile modulator of signaling affecting cellular adhesion, proliferation, survival, and cytokine/growth factor responses. Biochim Biophys Acta. 2006 Oct;1763(10):991-9. Haeryfar SM, Hoskin DW: Thy-1: more than a mouse pan-T cell marker. J Immunol. 2004 Sep 15;173(6):3581-8.
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	CD90;T25;Thy-1;thy-1 antigen;thy-1 membrane glycoprotein;Thy1.1;Thy1.2;Thy-1.2.
Similar products	CD90.2 / Thy-1.2
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Type	Monoclonal Antibody
Manufacturer - Category	Root Catalog/Products/Monoclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Gene symbol	Thy1
Gene Fullname	thymus cell antigen 1, theta
Product format	Phosphate buffered saline (PBS), pH 7.4
Reconstitution and storage	2°C to 8°C
Description of target	May play a role in cell-cell or cell-ligand interactions during synaptogenesis and other events in the brain.
Nucleotide accession_num	NM_009382.3
Protein accession_num	NP_033408.1
Protein name	Thy-1 membrane glycoprotein
Clonality	Monoclonal
Purification	Purified
Immunogen	thymocytes from C3H/Di mice (Thy-1.2 positive)
Manufacturer - Specificity	The mouse monoclonal antibody 1aG4/C5 recognizes alloantigen Thy-1.2 of mouse Thy-1 (CD90); it does not cross-react with Thy-1.1 alloantigen. Thy-1 is an 18-35 kDa cell surface GPI linked glycoprotein (immunoglobulin superfamily); in mouse it is abundant on thymocytes and peripheral T lymphocytes.
Formulation	Azide free
Concentration	1 mg/ml
Storage Buffer	Azide free phosphate buffered saline (PBS), preserved by filter sterilization, approx. pH 7.4

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Menge: 0.1 mg (C100)

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