Anti-GluR1

Root Catalog/Products/Monoclonal Antibodies, Root Catalog/Products/Monoclonal Antibodies/Pan Specific, Root Catalog/Products/Primary Antibodies

Wet Ice

The antibody has been directly tested for reactivity in Western blots with mouse and rat tissue.
Western blot of rat hippocampal lysate showing specific immunolabeling of the ~ 105k GluR1 protein.

Liquid. 100 ul in 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 ug per ml BSA and 50% glycerol. Adequate amount of material to conduct 10-mini Western Blots.

The ion channels activated by glutamate are typically divided into two classes. Those that are sensitive to N-methyl-D-aspartate (NMDA) are designated NMDA receptors (NMDAR) while those activated by alpha -amino-3-hydroxy-5-methyl-4-isoxalone propionic acid (AMPA) are known as AMPA receptors (AMPAR). The AMPAR are comprised of four distinct glutamate receptor subunits designated (GluR1-4) and they play key roles in virtually all excitatory neurotransmission in the brain (Keinänen et al., 1990; Hollmann and Heinemann, 1994).

Glutamate receptor 1

Protein G purified culture supernatant.

Mouse; Rat