MAP3K7 Antibody (Phospho-Thr187)

ArtNr	OAAB20471
Hersteller	AVIVA Systems Biology
Menge	100 ul
Kategorie	Oncology Neuroscience Neuroinflammation Antibodies By Cell Type Blastoma Carcinoma Glioma Hematology Lymphoma Myeloma Melanoma Sarcoma Cell Biology Cell Status Western Blot Senescence Primary Antibodies Dot Blot
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	WB
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Rabbit
Isotype	IgG
Citations	Sakurai H.,et al.Biochem. Biophys. Res. Commun. 243:545-549(1998). Dempsey C.E.,et al.Biochim. Biophys. Acta 1517:46-52(2000). Ota T.,et al.Nat. Genet. 36:40-45(2004). Mungall A.J.,et al.Nature 425:805-811(2003). Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	CSCF,FMD2,TAK1,MEKK7,TGF1a
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Polyclonal Antibodies/Phospho Specific, Root Catalog/Products/Primary Antibodies
Manufacturer - Isotype	Rabbit IgG
Manufacturer - Targets	Phospho-Thr187
Shipping Temperature	Wet Ice
Molecular Weight	67 kDa
Manufacturer - Application Additional Information	WB: 1:1000
Gene symbol	MAP3K7
Gene Fullname	mitogen-activated protein kinase kinase kinase 7
Product format	Liquid
Reconstitution and storage	Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
Description of target	The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL-1, this protein forms a kinase complex including TRAF6, MAP3K7P1/TAB1 and MAP3K7P2/TAB2; this complex is required for the activation of nuclear factor kappa B. This kinase can also activate MAPK8/JNK, MAP2K4/MKK4, and thus plays a role in the cell response to environmental stresses. Four alternatively spliced transcript variants encoding distinct isoforms have been reported.
Nucleotide accession_num	NM_003188.3
Protein accession_num	NP_003179.1
Clonality	Polyclonal
Homology	Human, Mouse
Formulation	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

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Menge: 100 ul

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Lieferung vsl. bis 30.10.2025