BAX Antibody

ArtNr	OAAB20920
Hersteller	AVIVA Systems Biology
Menge	100 ul
Kategorie	Oncology Antibodies By Cell Type Blastoma Carcinoma Hematology Leukemia Lymphoma Myeloma Cell Biology Cell Status Apoptosis Western Blot Autophagy Cardiovascular Research Ischemia & Reperfusion Injury Primary Antibodies By Organ Colorectal Cancer Testicular & Prostate Cancer
Typ	Antibody Monoclonal
Format	Liquid
Applikationen	WB
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Rabbit
Citations	Oltvai Z.N.,et al.Cell 74:609-619(1993). Apte S.S.,et al.Genomics 26:592-594(1995). Shi B.,et al.Biochem. Biophys. Res. Commun. 254:779-785(1999). Schmitt E.,et al.Biochem. Biophys. Res. Commun. 270:868-879(2000). Cartron P.F.,et al.Hum. Mol. Genet. 11:675-687(2002).
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	BCL2L4
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Type	Monoclonal Antibody
Manufacturer - Category	Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Molecular Weight	21 kDa
Manufacturer - Application Additional Information	WB: 1:1000
Gene symbol	BAX
Gene Fullname	BCL2-associated X protein
Product format	Liquid
Reconstitution and storage	Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
Description of target	The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for this gene.
Nucleotide accession_num	NM_001291428.1
Protein accession_num	NP_001278357.1
Clonality	Monoclonal
Homology	Human, Mouse
Formulation	Purified mouse monoclonal antibody in PBS (pH 7.4) containing with 0.02% sodium azide and 50% glycerol.

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OAAB20920-datasheet.pdf

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Menge: 100 ul

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Lieferung vsl. bis 25.12.2025

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