TIMP2 Antibody

ArtNr	OAAB22193
Hersteller	AVIVA Systems Biology
Menge	200 ul
Kategorie	Food Safety Allergenes Antibodies Immunohistochemistry Western Blot ELISA Primary Antibodies
Typ	Antibody Monoclonal
Format	Liquid
Applikationen	WB
Clon	1554CT494.262.47
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Mouse
Isotype	IgG1 Kappa
Citations	Stetler-Stevenson W.G.,et al.J. Biol. Chem. 265:13933-13938(1990). Boone T.C.,et al.Proc. Natl. Acad. Sci. U.S.A. 87:2800-2804(1990). Hammani K.,et al.J. Biol. Chem. 271:25498-25505(1996). Malik K.,et al.Submitted (AUG-1990) to the EMBL/GenBank/DDBJ databases. Stetler-Stevenson W.G.,et al.J. Biol. Chem. 264:17374-17378(1989).
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	DDC8,CSC-21K
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Type	Monoclonal Antibody
Manufacturer - Category	Root Catalog/Products/Primary Antibodies
Manufacturer - Isotype	IgG1, kappa
Shipping Temperature	Wet Ice
Molecular Weight	24 kDa
Manufacturer - Application Additional Information	IF: 1:25 FC: 1:25 IHC-P: 1:25 WB: 1:500 WB: 1:2000
Gene symbol	TIMP2
Gene Fullname	TIMP metallopeptidase inhibitor 2
Product format	Liquid
Reconstitution and storage	Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
Description of target	This gene is a member of the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. In addition to an inhibitory role against metalloproteinases, the encoded protein has a unique role among TIMP family members in its ability to directly suppress the proliferation of endothelial cells. As a result, the encoded protein may be critical to the maintenance of tissue homeostasis by suppressing the proliferation of quiescent tissues in response to angiogenic factors, and by inhibiting protease activity in tissues undergoing remodelling of the extracellular matrix.
Nucleotide accession_num	NM_003255.4
Protein accession_num	NP_003246.1
Clonality	Monoclonal
Purification	Protein G column purification, followed by dialysis against PBS
Immunogen	This TIMP2 antibody is generated from a mouse immunized with arecombinant protein of human TIMP2.
Homology	Human, Mouse
Formulation	Purified monoclonal antibody, supplied in PBS with 0.09% sodium azide.
Concentration	500 ug/mL

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