KRIT1 Antibody

ArtNr	OAAL00041
Hersteller	AVIVA Systems Biology
Menge	100 ug
Kategorie	Antibodies Cell Biology Cytoskeleton ELISA Primary Antibodies Immunostaining small GTPases Ras Subfamily Rap Subfamily
Typ	Antibody Monoclonal
Format	Liquid
Applikationen	ELISA
Clon	1D8
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Mouse
Isotype	IgG1 Kappa
Sequence	AAFFTGQIFTKASPSNHKVIPVYVGVNIKGLHLLNMETKALLISLKYGCFMWQLGDTDTCFQIHSMENKMSFIVHTKQAGLVVKLLMKLNGQLMPTERNS
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	ankyrin repeat-containing protein Krit1;CAM;CCM1;cerebral cavernous malformations 1 protein;krev interaction trapped 1;krev interaction trapped protein 1.
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Type	Monoclonal Antibody
Manufacturer - Category	Root Catalog/Products/Monoclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Gene symbol	KRIT1
Gene Fullname	KRIT1 ankyrin repeat containing
Product format	Liquid
Reconstitution and storage	Store at -20C or lower. Aliquot to avoid repeated freezing and thawing.
Description of target	This gene encodes a protein containing four ankyrin repeats, a band 4.1/ezrin/radixin/moesin (FERM) domain, and multiple NPXY sequences. The encoded protein is localized in the nucleus and cytoplasm. It binds to integrin cytoplasmic domain-associated protein-1 alpha (ICAP1alpha), and plays a critical role in beta1-integrin-mediated cell proliferation. It associates with junction proteins and RAS-related protein 1A (Rap1A), which requires the encoded protein for maintaining the integrity of endothelial junctions. It is also a microtubule-associated protein and may play a role in microtubule targeting. Mutations in this gene result in cerebral cavernous malformations. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq
Nucleotide accession_num	NM_004912
Protein accession_num	https://www.ncbi.nlm.nih.gov/protein/NP_004903
Protein name	Homo sapiens KRIT1, ankyrin repeat containing (KRIT1), transcript variant 2, mRNA\|krev interaction trapped protein 1 isoform 1 [Homo sapiens]
Clonality	Monoclonal
Immunogen	KRIT1 (NP_004903, 637 a.a. ~ 736 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Formulation	In 1x PBS, pH 7.4

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OAAL00041-datasheet.pdf

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Menge: 100 ug

lieferbar

Lieferung vsl. bis 25.12.2025

Express-Lieferung: 2 Tage sparen

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