CREBL2 Antibody

ArtNr	OAAL00059
Hersteller	AVIVA Systems Biology
Menge	100 ug
Kategorie	Oncology Neuroscience Molecular Targets for Neuroscience Neural Signaling Antibodies By Cell Type Carcinoma Hematology Leukemia Lymphoma Melanoma Sarcoma Western Blot ELISA Primary Antibodies Immunostaining
Typ	Antibody Monoclonal
Format	Liquid
Applikationen	WB, ELISA
Clon	1C1
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Mouse
Isotype	IgG2a
Sequence	MDDSKVVGGKVKKPGKRGRKPAKIDLKAKLERSRQSARECRARKKLRYQYLEELVSSRERAICALREELEMYKQWCMAMDQGKIPSEIKALLTGEEQNKSQQNSSRHTKAGKTDANSNSW
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	cAMP-responsive element-binding protein-like 2;MHBs-binding protein 1.
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Type	Monoclonal Antibody
Manufacturer - Category	Root Catalog/Products/Monoclonal Antibodies, Root Catalog/Products/Primary Antibodies
Manufacturer - Isotype	IgG_2a Kappa
Shipping Temperature	Wet Ice
Gene symbol	CREBL2
Gene Fullname	cAMP responsive element binding protein like 2
Product format	Liquid. PBS (pH 7.4)
Reconstitution and storage	Store at -20C or lower. Aliquot to avoid repeated freezing and thawing.
Description of target	cAMP response element (CRE)-binding protein-like-2 (CREBL2) was identified in a search to find genes in a commonly deleted region on chromosome 12p13 flanked by ETV6 and CDKN1B genes, frequently associated with hematopoietic malignancies, as well as breast, non-small-cell lung and ovarian cancers. CREBL2 shares a 41% identity with CRE-binding protein (CREB) over a 48-base long region which encodes the bZip domain of CREB. The bZip domain consists of about 30 amino acids rich in basic residues involved in DNA binding, followed by a leucine zipper motif involved in protein dimerization. This suggests that CREBL2 encodes a protein with DNA binding capabilities. The occurance of CREBL2 deletion in malignancy suggests that CREBL2 may act as a tumor suppressor gene. [provided by RefSeq
Nucleotide accession_num	NM_001310.2
Protein accession_num	https://www.ncbi.nlm.nih.gov/protein/NP_001301.1
Protein name	cAMP-responsive element-binding protein-like 2 [Homo sapiens]\|Homo sapiens cAMP responsive element binding protein like 2 (CREBL2), mRNA
Clonality	Monoclonal
Immunogen	CREBL2 (NP_001301.1, 1 a.a. ~ 120 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Concentration	1 mg/ml

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OAAL00059-datasheet.pdf

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Menge: 100 ug

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Lieferung vsl. bis 08.01.2026

Express-Lieferung: 1 Tage sparen

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