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APLP2 Antibody - C-terminal region

ArtNr OABB00999
Hersteller AVIVA Systems Biology
Menge 100 ug/vial
Kategorie
Typ Antibody Polyclonal
Format Liquid
Applikationen WB, FC, IF, IHC, ELISA
Specific against Human (Homo sapiens)
Host Rabbit
Isotype IgG
Konjugat/Tag Unconjugated
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias acyl-CoA (8-3)-desaturase;D5D;delta(5) desaturase;Delta(5) fatty acid desaturase;delta-5 fatty acid desaturase;FADS6;FADSD5;linoleoyl-CoA desaturase (delta-6-desaturase)-like 1;LLCDL1;TU12.
Lieferbar
Manufacturer - Type
Polyclonal Antibody
Manufacturer - Category
Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Gene symbol
FADS1
Gene Fullname
fatty acid desaturase 1
Product format
Liquid
Reconstitution and storage
-20°C or -80°C
Description of target
APLP2(Amyloid beta(A4) precursor-like protein 2), also known as CDEBP or SPERM MEMBRANE PROTEIN, is a protein that in humans is encoded by the APLP2 gene. The APLP2 gene is mapped on 11q24.3. The human amyloid precursor-like protein APLP2 is a highly conserved homolog of a sequence-specific DNA-binding mouse protein with an important function in the cell cycle. APLP2 along with APLP1 are important modulators of glucose and insulin homeostasis. APLP2 associates with antigen presentation molecules like MHC class I molecules and regulates their surface expression by enhancing endocytosis.
Protein name
Fatty acid desaturase 1
Clonality
Recombinant Monoclonal
Purification
Affinity Purified
Immunogen
A synthesized peptide derived from human FADS1
Dilution
Isoform 2 does not exhibit any catalytic activity toward 20:3n-6, but it may enhance FADS2 activity (By similarity). Isoform 1 is a component of a lipid metabolic pathway that catalyzes biosynthesis of highly unsaturated fatty acids (HUFA) from precursor essential polyunsaturated fatty acids (PUFA) linoleic acid (LA) (18:2n-6) and alpha-linolenic acid (ALA) (18:3n-3). Catalyzes the desaturation of dihomo-gamma-linoleic acid (DHGLA) (20:3n-6) and eicosatetraenoic acid (20:4n-3) to generate arachidonic acid (AA) (20:4n-6) and eicosapentaenoic acid (EPA)(20:5n-3), respectively.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug/vial
Lieferbar: In stock
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