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TNFRSF25 Antibody - N-terminal region

ArtNr OABB01154
Hersteller AVIVA Systems Biology
Menge 100 ug/vial
Kategorie
Typ Antibody Polyclonal
Format Liquid
Applikationen WB, IF, ELISA
Specific against Human (Homo sapiens)
Host Rabbit
Isotype IgG
Konjugat/Tag Unconjugated
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias ATP-dependent RNA helicase eIF4A-1;DDX2A;EIF4A;EIF-4A;eIF4A-I;eIF-4A-I;eukaryotic initiation factor 4AI;eukaryotic initiation factor 4A-I;eukaryotic translation initiation factor 4A.
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Manufacturer - Type
Polyclonal Antibody
Manufacturer - Category
Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Gene symbol
EIF4A1
Gene Fullname
eukaryotic translation initiation factor 4A1
Product format
Liquid
Reconstitution and storage
-20°C or -80°C
Description of target
TNFRSF25(Tumor Necrosis Factor Receptor Superfamily Member 25), also known as LARD, APO3, DR3 or TNFR25, is a protein that in humans is encoded by the TNFRSF25 gene. Members of the mammalian tumor necrosis factor receptor(TNFR) family are cell-surface proteins that interact with a corresponding TNF-related ligand family. By fluorescence in situ hybridization, Marsters et al.(1996) mapped the Apo3 gene to 1p36.3. Marsters et al.(1996) showed that ectopic expression of Apo3 in mammalian cells triggered apoptosis and activated the transcription factor NF-kappa-B. They suggested that, like TNFR1, Apo3 may regulate distinct signaling pathways in different cellular contexts.
Protein name
Eukaryotic initiation factor 4A-I
Clonality
Recombinant Monoclonal
Purification
Affinity Purified
Immunogen
A synthesized peptide derived from human eIF4A1
Dilution
ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug/vial
Lieferbar: In stock
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