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COL1A1 Antibody - C-terminal region

ArtNr OABB01300
Hersteller AVIVA Systems Biology
Menge 100 ug/vial
Kategorie
Typ Antibody Polyclonal
Format Liquid
Applikationen FC, ELISA
Specific against Human (Homo sapiens)
Host Rabbit
Isotype IgG
Konjugat/Tag Unconjugated
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias 2F1;CLEC15A;C-type lectin domain family 15 member A;ITIM-containing receptor MAFA-L;killer cell lectin-like receptor subfamily G member 1;killer cell lectin-like receptor subfamily G,member 1;MAFA;MAFA-2F1;MAFA-L;MAFA-LIKE;MAFA-like receptor;Mast cell function-associated antigen;mast cell function-associated antigen (ITIM-containing).
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Manufacturer - Type
Polyclonal Antibody
Manufacturer - Category
Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Gene symbol
KLRG1
Gene Fullname
killer cell lectin like receptor G1
Product format
Liquid
Reconstitution and storage
-20°C or -80°C
Description of target
Collagen, type I, alpha 1, also known as COL1A1, is a human gene that encodes the major component of type I collagen, the fibrillar collagen found in most connective tissues, including cartilage. This gene is mapped to 17q21.33. This gene encodes the pro-alpha1 chains of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIA, Ehlers-Danlos syndrome Classical type, Caffey Disease and idiopathic osteoporosis.
Protein name
Killer cell lectin-like receptor subfamily G member 1
Clonality
Recombinant Monoclonal
Purification
Affinity Purified
Immunogen
A synthesized peptide derived from human KLRG1
Dilution
Plays an inhibitory role on natural killer (NK) cells and T-cell functions upon binding to their non-MHC ligands. May mediate missing self recognition by binding to a highly conserved site on classical cadherins, enabling it to monitor expression of E-cadherin/CDH1, N-cadherin/CDH2 and R-cadherin/CDH4 on target cells.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug/vial
Lieferbar: In stock
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