VEGFA Antibody (OABB01536)

VEGFA

7422

VEGF, a homodimeric glycoprotein of relative molecular mass 45, 000, is the only mitogen that specifically acts on endothelial cells. It may be a major regulator of tumor angiogenesis in vivo. It is, however, structurally related to platelet-derived growth factor. VEGF shares homology with the PDGF A chain and B chain, including conservation of all 8 cysteines found in PDGFA and PDGFB. VEGF gene contains 8 exons. VEGF induces remodeling and enhances TH2-mediated sensitization and inflammation in the lung. And this gene also can regulate haematopoietic stem cell survival by an internal autocrine loop mechanism. Whata€s more, it also stimulates neurogenesis in vitro and in vivo.

Polyclonal