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NEUROPILIN 1 Antibody

ArtNr OABB01783
Hersteller AVIVA Systems Biology
Menge 100 ug/vial
Kategorie
Typ Antibody Polyclonal
Format Liquid
Applikationen WB, IF, IHC, ELISA
Specific against Human (Homo sapiens), Rat (Rattus norvegicus)
Host Rabbit
Isotype IgG
Konjugat/Tag Unconjugated
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias 17-alpha-hydroxyprogesterone aldolase;CPT7;CYP17;CYPXVII;cytochrome P450 17A1;cytochrome p450 XVIIA1;cytochrome P450,family 17,subfamily A,polypeptide 1;cytochrome P450,subfamily XVII (steroid 17-alpha-hydroxylase),adrenal hyperplasia;cytochrome P450c17;cytochrome P450-C17;P450C17;S17AH;steroid 17-alpha-hydroxylase/17,20 lyase;steroid 17-alpha-monooxygenase.
Lieferbar
Manufacturer - Type
Polyclonal Antibody
Manufacturer - Category
Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Gene symbol
CYP17A1
Gene Fullname
cytochrome P450 family 17 subfamily A member 1
Product format
Liquid
Reconstitution and storage
-20°C or -80°C
Description of target
This gene encodes one of two neuropilins, which contain specific protein domains which allow them to participate in several different types of signaling pathways that control cell migration. Neuropilins contain a large N-terminal extracellular domain, made up of complement-binding, coagulation factor V/VIII, and meprin domains. These proteins also contain a short membrane-spanning domain and a small cytoplasmic domain. Neuropilins bind many ligands and various types of co-receptors; they affect cell survival, migration, and attraction. Some of the ligands and co-receptors bound by neuropilins are vascular endothelial growth factor (VEGF) and semaphorin family members. Several alternatively spliced transcript variants that encode different protein isoforms have been described for this gene.
Protein name
Steroid 17-alpha-hydroxylase/17, 20 lyase
Clonality
Recombinant Monoclonal
Purification
Affinity Purified
Immunogen
A synthesized peptide derived from human Cytochrome P450 17A1
Dilution
Conversion of pregnenolone and progesterone to their 17-alpha-hydroxylated products and subsequently to dehydroepiandrosterone (DHEA) and androstenedione. Catalyzes both the 17-alpha-hydroxylation and the 17, 20-lyase reaction. Involved in sexual development during fetal life and at puberty.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug/vial
Lieferbar: In stock
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