LYRIC Antibody

ArtNr	OABB01821
Hersteller	AVIVA Systems Biology
Menge	100 ug/vial
Kategorie	Oncology Neuroscience Neuroinflammation Antibodies By Cell Type Blastoma Carcinoma Hematology Leukemia Lymphoma Myeloma Melanoma Sarcoma Flow Cytometry Immunohistochemistry Western Blot ELISA Immunofluorescence Primary Antibodies By Organ Bladder Cancer Immunostaining
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	WB, FC, IF, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	apoferritin;cell proliferation-inducing gene 15 protein;ferritin H subunit;ferritin heavy chain;ferritin,heavy polypeptide 1;FHC;FTH;FTHL6;HFE5;PIG15;placenta immunoregulatory factor;PLIF;proliferation-inducing protein 15.
Lieferbar
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Gene symbol	FTH1
Gene Fullname	ferritin heavy chain 1
Product format	Liquid
Reconstitution and storage	-20°C or -80°C
Description of target	MTDH (Metadherin), also known as protein LYRIC or astrocyte elevated gene-1 protein (AEG-1) is a protein that in humans is encoded by the MTDH gene. AEG-1 is involved in HIF-1alpha mediated angiogenesis. AEG-1 also interacts with SND1 and involved in RNA-induced silencing complex (RISC) and plays very important role in RISC and miRNA functions. AEG-1 induces an oncogene called Late SV40 factor (LSF/TFCP2) which is involved in thymidylate synthase (TS) induction and DNA biosynthesis synthesis. Late SV40 factor (LSF/TFCP2) enhances angiogenesis by transcriptionally up-regulating matrix metalloproteinase-9 (MMP9). AEG-1 acts as an oncogene in melanoma, malignant glioma, breast cancer and hepatocellular carcinoma. It is highly expressed in these cancers and helps in progression and development of these cancers. It is induced by c-Myc oncogene and plays very important role in anchorage independent growth of cancer cells.
Protein name	Ferritin heavy chain
Clonality	Recombinant Monoclonal
Purification	Affinity Purified
Immunogen	A synthesized peptide derived from Human FTH1
Dilution	Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney (By similarity).

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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OABB01821-datasheet.pdf

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Menge: 100 ug/vial

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Lieferung vsl. bis 25.12.2025

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