PKC DELTA Antibody

ArtNr	OABB02110
Hersteller	AVIVA Systems Biology
Menge	100 ug/vial
Kategorie	Oncology Metabolism Diabetes Antibodies By Cell Type Blastoma Carcinoma Glioma Hematology Lymphoma Myeloma Melanoma Sarcoma Adenocarcinoma Flow Cytometry Western Blot ELISA Primary Antibodies Immunostaining
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	WB, FC, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	COX1;COX3;cyclooxygenase-1;PCOX1;PES-1;PGG/HS;PGH synthase 1;PGHS1;PGHS-1;PHS1;prostaglandin G/H synthase 1;prostaglandin H2 synthase 1;Prostaglandin-endoperoxide synthase 1;prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase);PTGHS.
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Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Gene symbol	PTGS1
Gene Fullname	prostaglandin-endoperoxide synthase 1
Product format	Liquid
Reconstitution and storage	-20°C or -80°C
Description of target	Protein kinase C delta type, also called PKCD, is an enzyme that in humans is encoded by the PRKCD gene. The PRKCD gene encodes a member of the protein kinase C family, members of which are critical for regulation of cell survival, proliferation, and apoptosis. This gene is mapped to 3p21.1. Studies both in human and mice demonstrate that this kinase is involved inB cell signaling and in the regulation of growth, apoptosis, and differentiation of a variety of cell types. PRKCD is also regulated by phosphorylation on various tyrosine residues including Y311 (by SRC). It has been showed that PRKCD phosphorylates NLRC4 and that this phosphorylation is critical for inflammasome assembly. Whata€s more, it is also a part of a noncanonical WNT signaling cascade.
Protein name	Prostaglandin G/H synthase 1
Clonality	Recombinant Monoclonal
Purification	Affinity Purified
Immunogen	A synthesized peptide derived from human COX1
Dilution	Converts arachidonate to prostaglandin H2 (PGH2), a committed step in prostanoid synthesis. Involved in the constitutive production of prostanoids in particular in the stomach and platelets. In gastric epithelial cells, it is a key step in the generation of prostaglandins, such as prostaglandin E2 (PGE2), which plays an important role in cytoprotection. In platelets, it is involved in the generation of thromboxane A2 (TXA2), which promotes platelet activation and aggregation, vasoconstriction and proliferation of vascular smooth muscle cells.

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OABB02110-datasheet.pdf

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Menge: 100 ug/vial

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Lieferung vsl. bis 25.12.2025

Express-Lieferung: 2 Tage sparen

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