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ATG16L1 Antibody (Phospho-Ser287) (OABF01536-100UL)

ATG16L1 Antibody (Phospho-Ser287) (OABF01536-100UL)

ArtNr	OABF01536
Hersteller	AVIVA Systems Biology
Menge	100 ul
Kategorie	Neuroscience Protein Aggregation, Clearance & Misfolding Antibodies Cell Biology Cell Status Immunohistochemistry Western Blot ELISA Immunofluorescence Immunocytochemistry Autophagy Primary Antibodies Immunostaining Immunochemistry
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	WB, IF, IHC, ICC, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus), Rabbit (Oryctolagus cuniculus), Horse (Equine), Cattle (Bovine)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	APG16L;APG16L beta;APG16-like 1;ATG16 autophagy related 16-like 1;ATG16A;ATG16L;autophagy-related protein 16-1;IBD10;WD repeat domain 30;WDR30.
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Applications	Enzyme-linked immunosorbent assay\|Immunocytochemistry\|Immunofluorescence\|Immunohistochemistry-Frozen\|Immunohistochemistry-Paraffin\|Western blot
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Polyclonal Antibodies/Phospho Specific, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Manufacturer - Application Additional Information	WB: 1:100 - 1000 IHC-P: : 1:100 - 500
Gene symbol	ATG16L1
Gene Fullname	autophagy related 16 like 1
Product format	Liquid. Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide.
Reconstitution and storage	-20°C
Description of target	Plays an essential role in autophagy: interacts with ATG12-ATG5 to mediate the conjugation of phosphatidylethanolamine (PE) to LC3 (MAP1LC3A, MAP1LC3B or MAP1LC3C), to produce a membrane-bound activated form of LC3 named LC3-II. Thereby, controls the elongation of the nascent autophagosomal membrane (PubMed:24553140, PubMed:23376921, PubMed:24954904, PubMed:27273576, PubMed:23392225). Regulates mitochondrial antiviral signaling (MAVS)-dependent type I interferon (IFN-I) production (PubMed:25645662). Negatively regulates NOD1- and NOD2-driven inflammatory cytokine response (PubMed:24238340). Instead, promotes with NOD2 an autophagy-dependent antibacterial pathway (PubMed:20637199). Plays a role in regulating morphology and function of Paneth cell (PubMed:18849966).
Protein name	Autophagy-related protein 16-1
Clonality	Polyclonal
Purification	Protein A Purified
Immunogen	KLH conjugated Synthesised phosphopeptide derived from human ATG16A/ATG16L1 around the phosphorylation site of Ser287
Concentration	1 ug/ul

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OABF01536-datasheet.pdf

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Menge: 100 ul

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Lieferung vsl. bis 25.12.2025

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