MCM3 Antibody

ArtNr	OACA02425
Hersteller	AVIVA Systems Biology
Menge	100 ul
Kategorie	Neuroscience Neural Lineage Markers Antibodies Immunohistochemistry Immunoprecipitation Western Blot ELISA Immunofluorescence Primary Antibodies CHiP Immunostaining
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	WB, IHC, ELISA, CHIP
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
Citations	[1] A role for the Ankyrin repeat containing protein Ankrd17 in Nod1- and Nod2-mediated inflammatory responses. Menning M., Kufer T.A.FEBS Lett. 587:2137-2142 (2013). [2] N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB. Van Damme P., Lasa M., Polevoda B., Gazquez C., Elosegui-Artola A., Kim D.S., De Juan-Pardo E., Demeyer K., Hole K., Larrea E., Timmerman E., Prieto J., Arnesen T., Sherman F., Gevaert K., Aldabe R.Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454 (2012). [3] Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features. Bienvenut W.V., Sumpton D., Martinez A., Lilla S., Espagne C., Meinnel T., Giglione C.Mol. Cell. Proteomics 11:M111.015131-M111.015131 (2012).
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	cervical cancer proto-oncogene 5;DNA polymerase alpha holoenzyme-associated protein P1;DNA replication factor MCM3;DNA replication licensing factor MCM3;HCC5;hRlf beta subunit;MCM3 minichromosome maintenance deficient 3;minichromosome maintenance deficient 3;P1.h;p102;P1-MCM3;replication licensing factor,beta subunit;RLF subunit beta;RLFB.
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Molecular Weight	91 kDa
Application Data	WB:1:200-1000, IHC:1:20-1:200
Gene symbol	MCM3
Gene Fullname	minichromosome maintenance complex component 3
Protein size	808
Product format	Liquid
Reconstitution and storage	-20°C or -80°C
Description of target	Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. Required for DNA replication and cell proliferation.
Nucleotide accession_num	NM_001270472.1
Protein accession_num	NP_001257401.1
Protein name	DNA replication licensing factor MCM3
Clonality	Polyclonal
Purification	Affinity Purified
Immunogen	Recombinant Human DNA replication licensing factor MCM3 protein (1-295AA)
Homology	Human
Manufacturer - Specificity	Human
Formulation	Provided in PBS, pH 7.3, 50% Glycerol, 0.02% Sodium Azide

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