FCMR Antibody

ArtNr	OACA02945
Hersteller	AVIVA Systems Biology
Menge	50 ug
Kategorie	Oncology Neuroscience Neuroinflammation Metabolism Diabetes Antibodies By Cell Type Blastoma Carcinoma Hematology Leukemia Lymphoma Myeloma Cell Biology Obesity Cell Culture Cytokines Cell Status Necrosis Apoptosis Immunohistochemistry Western Blot ELISA Autophagy Primary Antibodies By Organ Colorectal Cancer Testicular & Prostate Cancer Immunostaining
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	WB, ELISA
Specific against	Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
Citations	[1]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004). [2]"The transcriptional landscape of the mammalian genome." Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J. expand/collapse author list Hayashizaki Y. Science 309:1559-1563(2005) . [3]Song Y., Jacob C.O. Submitted (JAN-2003).
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	1810037B05Rik;Fai;Faim3;fas apoptotic inhibitory molecule 3;Fcmu;FcmuR;IgM Fc fragment receptor;regulator of Fas-induced apoptosis Toso;Toso.
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Gene symbol	Fcmr
Gene Fullname	Fc fragment of IgM receptor
Product format	Liquid
Reconstitution and storage	-20°C or -80°C
Description of target	May play a role in the immune system processes. Protects cells from FAS-, TNF alpha- and FADD-induced apoptosis without increasing expression of the inhibitors of apoptosis BCL2 and BCLXL. Seems to activate an inhibitory pathway that prevents CASP8 activation following FAS stimulation, rather than blocking apoptotic signals downstream. May inhibit FAS-induced apoptosis by preventing CASP8 processing through CFLAR up-regulation (By similarity).
Nucleotide accession_num	NM_026976
Protein accession_num	NP_081252
Protein name	Fas apoptotic inhibitory molecule 3
Clonality	Polyclonal
Purification	Protein G Purified
Immunogen	Recombinant Mouse Fas apoptotic inhibitory molecule 3 protein (18-262AA)
Formulation	50% Glycerol, 0.01M PBS, PH 7.4

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