HNRNPL Antibody

ArtNr	OACA03112
Hersteller	AVIVA Systems Biology
Menge	50 ug
Kategorie	Oncology Neuroscience Molecular Targets for Neuroscience Antibodies Immunohistochemistry Western Blot ELISA Immunofluorescence Primary Antibodies By Organ Lung Cancer Immunostaining
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	IF, IHC, ELISA
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
Citations	[1]"Complete sequencing and characterization of 21,243 full-length human cDNAs." Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. Sugano S.Nat. Genet. 36:40-45(2004). [2]"Molecular basis of T cell-mediated recognition of pancreatic cancer cells." Ito M., Shichijo S., Tsuda N., Ochi M., Harashima N., Saito N., Itoh K. Cancer Res. 61:2038-2046(2001). [3]"Human AP-endonuclease 1 and hnRNP-L interact with a nCaRE-like repressor element in the AP-endonuclease 1 promoter."Kuninger D.T., Izumi T., Papaconstantinou J., Mitra S.Nucleic Acids Res. 30:823-829(2002).
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	epididymis secretory sperm binding protein;heterogeneous nuclear ribonucleoprotein L;hnRNP L;hnRNP-L;HNRPL;P/OKcl.14.
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Gene symbol	HNRNPL
Gene Fullname	heterogeneous nuclear ribonucleoprotein L
Product format	Liquid
Reconstitution and storage	-20°C or -80°C
Description of target	Splicing factor binding to exonic or intronic sites and acting as either an activator or repressor of exon inclusion. Exhibits a binding preference for CA-rich elements (PubMed:11809897, PubMed:22570490, PubMed:24164894, PubMed:25623890, PubMed:26051023). Component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes and associated with most nascent transcripts (PubMed:2687284). Associates, together with APEX1, to the negative calcium responsive element (nCaRE) B2 of the APEX2 promoter (PubMed:11809897).
Nucleotide accession_num	NM_001005335
Protein accession_num	NP_001005335
Protein name	Heterogeneous nuclear ribonucleoprotein L
Clonality	Polyclonal
Purification	Protein G Purified
Immunogen	Recombinant Human Heterogeneous nuclear ribonucleoprotein L protein (89-335AA)
Formulation	50% Glycerol, 0.01M PBS, PH 7.4

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