PTPN5 Antibody

ArtNr	OACA03520
Hersteller	AVIVA Systems Biology
Menge	50 ug
Kategorie	Oncology Neuroscience Molecular Targets for Neuroscience Antibodies By Cell Type Blastoma Carcinoma Glioma Hematology Lymphoma Myeloma Melanoma Sarcoma Adenocarcinoma Immunohistochemistry Western Blot ELISA Immunocytochemistry Primary Antibodies Immunostaining
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	WB, IHC, ELISA
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
Citations	[1]"Crystal structures and inhibitor identification for PTPN5, PTPRR and PTPN7: a family of human MAPK-specific protein tyrosine phosphatases." Eswaran J., von Kries J.P., Marsden B., Longman E., Debreczeni J.E., Ugochukwu E., Turnbull A., Lee W.H., Knapp S., Barr A.J. Biochem. J. 395:483-491(2006). [2]"Dephosphorylation of specific sites in the kinase-specificity sequence domain leads to ubiquitin-mediated degradation of the tyrosine phosphatase STEP." Mukherjee S., Poddar R., Deb I., Paul S. Biochem. J. 440:115-125(2011). [3]"Molecular cloning of the human homolog of a striatum-enriched phosphatase (STEP) gene and chromosomal mapping of the human and murine loci." Li X., Luna J., Lombroso P.J., Francke U. Genomics 28:442-449(1995).
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	neural-specific protein-tyrosine phosphatase;protein tyrosine phosphatase,non-receptor type 5 (striatum-enriched);protein-tyrosine phosphatase striatum-enriched;PTPSTEP;STEP;STEP61;striatal-enriched protein tyrosine phosphatase;striatum-enriched protein-tyrosine phosphatase;tyrosine-protein phosphatase non-receptor type 5.
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Gene symbol	PTPN5
Gene Fullname	protein tyrosine phosphatase non-receptor type 5
Product format	Liquid
Reconstitution and storage	-20°C or -80°C
Description of target	May regulate the activity of several effector molecules involved in synaptic plasticity and neuronal cell survival, including MAPKs, Src family kinases and NMDA receptors.
Nucleotide accession_num	NM_001039970
Protein accession_num	NP_001035059
Protein name	RecName: Full=Tyrosine-protein phosphatase non-receptor type 5; AltName: Full=Neural-specific protein-tyrosine phosphatase; AltName: Full=Striatum-enriched protein-tyrosine phosphatase; Short=STEP\|Tyrosine-protein phosphatase non-receptor type 5
Clonality	Polyclonal
Purification	Protein G Purified
Immunogen	Recombinant Human Tyrosine-protein phosphatase non-receptor type 5 protein (300-555AA)
Formulation	50% Glycerol, 0.01M PBS, PH 7.4

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Menge: 50 ug

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Lieferung vsl. bis 08.01.2026