CIART Antibody

ArtNr	OACA05770
Hersteller	AVIVA Systems Biology
Menge	50 ug
Kategorie	Oncology Neuroscience Molecular Targets for Neuroscience Antibodies By Cell Type Blastoma Carcinoma Hematology Leukemia Lymphoma Sarcoma Immunohistochemistry ELISA Primary Antibodies Immunostaining
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	IHC, ELISA
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
Purity	> 95%
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	C1orf51;chIP-derived repressor of network oscillator;CHRONO;circadian-associated transcriptional repressor;computationally highlighted repressor of the network oscillator;GM129.
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Manufacturer - Application Additional Information	IHC: 1:20~200
Gene symbol	CIART
Gene Fullname	circadian associated repressor of transcription
Product format	Liquid
Reconstitution and storage	-20°C or -80°C
Description of target	Transcriptional repressor which forms a negative regulatory component of the circadian clock and acts independently of the circadian transcriptional repressors: CRY1, CRY2 and BHLHE41. In a histone deacetylase-dependent manner represses the transcriptional activator activity of the CLOCK-ARNTL/BMAL1 heterodimer. Abrogates the interaction of ARNTL/BMAL1 with the transcriptional coactivator CREBBP and can repress the histone acetyl-transferase activity of the CLOCK-ARNTL/BMAL1 heterodimer, reducing histone acetylation of its target genes. Rhythmically binds the E-box elements (5'-CACGTG-3') on circadian gene promoters and its occupancy shows circadian oscillation antiphasic to ARNTL/BMAL1. Interacts with the glucocorticoid receptor (NR3C1) and contributes to the repressive function in the glucocorticoid response (By similarity).
Nucleotide accession_num	NM_001300838
Protein accession_num	NP_001287767
Protein name	Circadian-associated transcriptional repressor
Clonality	Polyclonal
Purification	Protein G Purified
Immunogen	Recombinant Human Circadian-associated transcriptional repressor protein (1-385AA)
Formulation	50% Glycerol, 0.01M PBS, PH 7.4
Concentration	Varies by lot. See vial for concentration.

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OACA05770-datasheet.pdf

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Menge: 50 ug

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Lieferung vsl. bis 25.12.2025

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